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2013 Fiscal Year Final Research Report

Decomposition between cornea stiffness and eye pressure based stiffness through non-invasive dynamic active sensing

Research Project

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Project/Area Number 21246043
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionOsaka University

Principal Investigator

KANEKO MAKOTO  大阪大学, 工学(系)研究科(研究院), 教授 (70224607)

Co-Investigator(Kenkyū-buntansha) HIGASHIMORI Mitsuru  大阪大学, 大学院・工学研究科, 准教授 (30346522)
YAMADA Kenji  大阪大学, 大学院・医学研究科, 准教授 (70364114)
Co-Investigator(Renkei-kenkyūsha) KIUCHI Yoshiaki  広島大学, 大学院・医歯薬学研究科, 教授 (40214738)
Project Period (FY) 2009-04-01 – 2014-03-31
Keywords非接触センシング / 非侵襲 / ダイナミックセンシング / 眼計測 / 緑内障 / 眼剛性
Research Abstract

By measuring the deformation of cornea surface during the impartment of air-puff to eye, the correlation of the eye stiffness and eye pressure was evaluated. Through five-years-research, the following points were made clear. (1) The deformation under the air-puff becomes larger for senior subjects rather than young ones. (2) The curvature under an air-puff becomes larger for senior subjects rather than young ones. (3) After vitreous surgery, the eye ball deforms ellipsoidal when an air-puff is given to eye. (4) The stiffness of retina of glaucoma patient becomes higher than that of normal subject. (5) The eye pressure under contact lens is predictable by considering the shape of the lens.

  • Research Products

    (11 results)

All 2014 2013 2012 2011 2010 Other

All Journal Article (10 results) Remarks (1 results)

  • [Journal Article] Ocular Surface Displacement with and without Contact Lenses during Non-Contact Tonometry2014

    • Author(s)
      Rimayanti U., Kuchi Y., Umemura S., Takenaka J., Mochizuki H., and Kaneko M
    • Journal Title

      PLOS ONE

    • DOI

      10.1371/journal.pone.0096066

  • [Journal Article] Influence of Occular Stiffness on Intraocular Pressure Estimation Using Goldmann Applanation Tonometry2013

    • Author(s)
      Shirane M., Kiuchi Y., Otani K., Kaneko M., and Takenaka J
    • Journal Title

      Journal of Medical and Biological Engineering

      Volume: vol.33 Pages: 293-300

    • DOI

      10.5405/jmbe.1381

  • [Journal Article] Evaluation of Cornea Displacement using High-Speed Photography at the Early and Late Phases of Noncontact Tonometry2013

    • Author(s)
      Nakakura S., Kiuchi Y., Kaneko M., Mochizuki H., Yamada K., Kimura Y., Tabuchi H
    • Journal Title

      Investigative Ophthalmology and Visual Science

      Volume: vol.54 Pages: 2474-2481

    • DOI

      10.1167/ivos.12-11424

  • [Journal Article] 眼球内力学特性評価のための新しい力学的指標2013

    • Author(s)
      木村 洋介, 金子 真, 相澤 奈帆子, 田中 佑治, 國方 彦志, 中澤 徹
    • Journal Title

      日本機械学会論文集

      Volume: vol.79 Pages: 450-458

  • [Journal Article] コンタクトレンズ装着による眼圧計測ファントム現象の考察2013

    • Author(s)
      木村 洋介, 金子 真, 山 田 憲嗣, 木内 良明
    • Journal Title

      Imin KAO

      Volume: vol.79 Pages: 450-458

  • [Journal Article] Corneal Displacement during Tonometry with a Noncontact Tonometer2012

    • Author(s)
      Yoshiaki Kiuchi, Makoto Kaneko, Hideki Mochizuki, Joji Takenaka, Kenji Yamada, Junko Tanaka
    • Journal Title

      Jpn J Ophthalmol

      Volume: (Published online)

  • [Journal Article] Modeling, Sensing and Interpretation of Viscoelastic Contact Interface2012

    • Author(s)
      C. Tsai, I. Kao, M. Higashimori, and M. Kaneko
    • Journal Title

      Journal of Advanced Robotics

      Volume: vol. 26, no. 11-12 Pages: 1393-1418

  • [Journal Article] 空気噴流印加時の曲率に着目した角膜剛性 のエイジング評価2011

    • Author(s)
      五所卓巳, 山田憲嗣, 東森充, 金子真, 竹中丈二, 木内良明, 戸田良太郎, 西田幸二
    • Journal Title

      生体医工学

      Volume: vol. 49, no. 3 Pages: 469-475

  • [Journal Article] Noncontact Active Sensing for Viscoelastic Parameters of Tissue with Coupling Effect2011

    • Author(s)
      Nobuyuki Tanaka, Mitsuru Higashimori, Makoto Kaneko, and Imin Kao
    • Journal Title

      IEEE Transactions on Biomedical Engineering

      Volume: vol. 58, no. 4 Pages: 509-520

  • [Journal Article] Design of Noncontact Tumor Imager for Video-Assisted Thoracic Surgery2010

    • Author(s)
      Tomohiro Kawahara, Yoshihiro Miyata, Koichi Akayama, Masazumi Okajima, and Makoto Kaneko
    • Journal Title

      IEEE Transactions on Mechatronics

      Volume: vol. 15, no. 6 Pages: 838-846

  • [Remarks]

    • URL

      https://sites.google.com/site/osakaubiomarker/

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Published: 2015-06-25  

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