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2011 Fiscal Year Final Research Report

Comprehensive researches on fish energy metabolism control factors and development of methods for energy metabolism control

Research Project

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Project/Area Number 21248027
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Fisheries chemistry
Research InstitutionThe University of Tokyo (2010-2011)
Tokyo University of Marine Science and Technology (2009)

Principal Investigator

USHIO Hideki  東京大学, 大学院・農学生命科学研究科, 准教授 (50251682)

Co-Investigator(Kenkyū-buntansha) WATABE Shugo  東京大学, 大学院・農学生命科学研究科, 教授研究者 (40111489)
KANEKO Gen  東京大学, 大学院・農学生命科学研究科, 助教 (30466809)
HIRONO Ikuo  東京海洋大学, 大学院・海洋科学研究科, 教授 (00270926)
KONDO Hidehiro  東京海洋大学, 大学院・海洋科学研究科, 准教授 (20314635)
NAGASAKA Reiko  東京海洋大学, 大学院・海洋科学研究科, 助教 (90444132)
Project Period (FY) 2009 – 2011
Research Abstract

Control mechanisms of fish energy metabolisms were investigated. Gamma-oryzanol administration is useful for accelerating growth of culture fish through the induction of energy productions from carbohydrates and lipids.

  • Research Products

    (30 results)

All 2012 2011 2010

All Journal Article (12 results) Presentation (12 results) Book (1 results) Patent(Industrial Property Rights) (5 results)

  • [Journal Article] γ-Oryzanol reduces adhesion molecule expression in vascular endothelial cells via suppression of nuclear factor-κB activation2012

    • Author(s)
      Sakai S, Murata T, Tsubosaka Y, Ushio H, Hori M, Ozaki H
    • Journal Title

      J Agric Food Chem

      Volume: 60 Pages: 3367-3372

    • DOI

      doi:10.1021/jf2043407.

  • [Journal Article] EST analysis on adipose tissue of rainbow trout Oncorhynchus mykiss and tissue distribution of adiponectin2011

    • Author(s)
      Kondo H, Suga R, Suda S, Nozaki R, Hirono I, Nagasaka R, Kaneko G, Ushio H, Watabe S
    • Journal Title

      Gene

      Volume: 485 Pages: 40-45

    • DOI

      doi:10.1016/j.gene.2011.05.035.

  • [Journal Article] γ-オリザノールの添加がアスタキサンチン含有飼料によるブリ切り身の変色抑制作用に及ぼす影響2011

    • Author(s)
      長阪玲子, 風間貴充, 潮秀樹, 坂本浩志, 坂本憲一
    • Journal Title

      日本水産学会誌

      Volume: 77 Pages: 1101-1104

    • DOI

      doi:10.2331/suisan.77.1101.

  • [Journal Article] Accumulation of gamma-oryzanol in teleost2011

    • Author(s)
      Nagasaka R, Kazama T, Ushio H, Sakamoto H, Sakamoto K, Satoh S
    • Journal Title

      Fish. Sci

      Volume: 77 Pages: 431-438

    • DOI

      doi:10.1007/s12562-011-0336-9.

  • [Journal Article] Biological abilities of rice bran-derived antioxidant phytochemicals for medical therapy2011

    • Author(s)
      Islam Md, Nagasaka R, Ohara K, Hosoya T, Ozaki H, Ushio H, Hori M
    • Journal Title

      Current Topics in Medical Chemistry

      Volume: 11 Pages: 1847-1853

    • DOI

      doi:10.2174/156802611796235099.

  • [Journal Article] γ-Oryzanol recovers mouse hypoadiponectinemia induced by animal fat ingestion2011

    • Author(s)
      Nagasaka R, Yamasaki T, Uchida A, Ohara K, Ushio H
    • Journal Title

      Phytomedicine

      Volume: 18 Pages: 655-660

    • DOI

      doi:10.1016/j.phymed.2011.01.004

  • [Journal Article] Oral administration ofγ-aminobutyric acid andγ-oryzanol prevents stress-induced hypoadiponectinemia2011

    • Author(s)
      Ohara K, Kiyotani Y, Uchida A, Nagasaka R, Maehara H, Kanemoto S, Hori M, Ushio H
    • Journal Title

      Phytomedicine

      Volume: 18 Pages: 669-671

    • DOI

      doi:10.1016/j.phymed.2011.01.003.

  • [Journal Article] cDNA cloning of two types of growth hormone receptor in torafugu Takifugu rubripes : tissue distribution is possibly correlated to lipid accumulation patterns2011

    • Author(s)
      Hirano Y, Kaneko G, Koyama H, Ushio H, Watabe S
    • Journal Title

      Fish. Sci

      Volume: 77 Pages: 855-865

    • DOI

      doi:10.1007/s12562-011-0377-0.

  • [Journal Article] Constitutive expression of insulin receptor substrate(IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts2011

    • Author(s)
      Hakuno F, Yamauchi Y, Kaneko G, Yoneyama Y, Nakae J, Chida K, Kadowaki T, Yamanouchi K, Nishihara M, Takahashi S
    • Journal Title

      PLoS ONE

      Volume: 6 Pages: e025655

    • DOI

      doi:10.1371/journal.pone.0025655.

  • [Journal Article] Correlation with larval body size of mRNA levels of growth hormone, growth hormone receptor I and insulin-like growth factor I in larval torafugu Takifugu rubripes2011

    • Author(s)
      Kaneko G, Furukawa S, Kurosu Y, Yamada T, Takeshima H, Nishida M, Mitsuboshi T, Otaka T, Shirasu K, Koda T, Takemasa Y, Aki S, Mochizuki T, Fukushima H, Fukuda Y, Kinoshita S, Asakawa S, Watabe S
    • Journal Title

      J. Fish Biol.

      Volume: 79 Pages: 854-874

    • DOI

      doi:10.1111/j.1095-8649.2011.03037.x.

  • [Journal Article] Efficacy of silkworm(Bombyx mori L.) chrysalis oil as a lipid source in adult Wistar rats2011

    • Author(s)
      Mentang F, Maita M, Ushio H, Ohshima T
    • Journal Title

      Food Chem

      Volume: 127 Pages: 899-904

    • DOI

      doi:10.1016/j.foodchem.2011.01.045.

  • [Journal Article] Linear chain aldehydes evoke calcium responses in B16 melanoma cells2011

    • Author(s)
      Ishikawa Y, Ohara K, Ohshima T, Ushio H
    • Journal Title

      EXCLI J

      Volume: 10 Pages: 303-311

    • URL

      http://www.excli.de/vol10/Ishikawa_Ushio12_2011/Ishikawa_Ushio_09122011_proof.pdf

  • [Presentation] Regulation of peroxisome proliferator-activated receptor activity by target of rapamycin and amino acids in teleost2012

    • Author(s)
      長阪玲子,植木瑞葵,飯野翔太,潮秀樹,近藤秀裕,廣野育生,金子元,渡部終五
    • Organizer
      BMB2010
    • Year and Date
      2012-12-07
  • [Presentation] Physiological functions of gamma-oryzanol and application of gamma-oryzanol to fish cultures2011

    • Author(s)
      Ushio H
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Year and Date
      2011-10-28
  • [Presentation] Studies on the species-specific lipid accumulation in torafugu and red seabream2011

    • Author(s)
      Kaneko G
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Year and Date
      2011-10-28
  • [Presentation] 発現配列タグ(EST)を利用したトラフグおよびマダイのアポリポタンパク質の発現様式の比較2011

    • Author(s)
      金子元、近藤秀裕、廣野育生、長阪玲子、佐藤秀一、潮秀樹、渡部終五
    • Organizer
      平成23年度日本水産学会秋季大会
    • Year and Date
      2011-09-29
  • [Presentation] マダイ各組織におけるリポタンパク質リパーゼ活性2011

    • Author(s)
      白神裕人、金子元、Anurak Khieokhajonkhet、平野雪、潮秀樹、佐藤秀一、渡部終五
    • Organizer
      平成23年度日本水産学会秋季大会
    • Year and Date
      2011-09-29
  • [Presentation] ニジマス脂肪組織で発現する遺伝子の網羅的解析2011

    • Author(s)
      近藤秀裕・廣野育生・長阪玲子・金子元・潮秀樹・渡部終五
    • Organizer
      平成22年度日本水産学会秋期大会
    • Year and Date
      2011-09-23
  • [Presentation] Regulatory mechanisms of amino acid metabolism in teleost2011

    • Author(s)
      Reiko Nagasaka, Mizuki Ueki, Hidehiro Kondo, Ikuo Hirono, Gen Kaneko, Shugo Watabe, Hideki Ushio
    • Organizer
      第84回日本生化学会大会
    • Year and Date
      2011-09-22
  • [Presentation] EFFECTS OF FEED RESTRICTION ON GENE EXPRESSION PROFILES OF ADIPONECTIN AND ENERGY METABOLISM GENES IN RAINBOW TROUT ONCORHYNCHUS MYKISS MUSCLE2011

    • Author(s)
      Kondo H, Suda S, Kawana Y, Hirono I, Nagasaka R, Kaneko G, Ushio H, Watabe S
    • Organizer
      Genomics in Aquaculture
    • Year and Date
      2011-09-14
  • [Presentation] 魚類におけるアミノ酸代謝の制御機構に関する基礎研究22011

    • Author(s)
      植木瑞葵,長阪玲子,近藤秀裕,廣野育生,金子元,渡部終五,潮秀樹
    • Organizer
      平成23年度日本水産学会春季大会
    • Year and Date
      2011-03-30
  • [Presentation] 魚類におけるアミノ酸代謝の制御機構に関する基礎研究2010

    • Author(s)
      長阪玲子,植木瑞葵,潮秀樹,近藤秀裕,廣野育生,金子元,渡部終五
    • Organizer
      平成22年度日本水産学会秋季大会,講演要旨集
    • Year and Date
      20100922-25
  • [Presentation] ガンマオリザノールによるmTORの活性抑制に関する研究2010

    • Author(s)
      小林由佳,飯野翔太,長阪玲子,潮秀樹
    • Organizer
      BMB2010
    • Year and Date
      2010-12-07
  • [Presentation] ニジマスアディポネクチンの構造および発現2010

    • Author(s)
      菅亮太、近藤秀裕、青木宙、廣野育生
    • Organizer
      第12回マリンバイオテクノロジー学会
    • Year and Date
      2010-05-30
  • [Book] 沿岸漁獲物の高品質化「魚類のエネルギー代謝に及ぼす水温および飢餓の影響」2012

    • Author(s)
      金子元,潮秀樹,渡部終五
    • Total Pages
      168
    • Publisher
      恒星社厚生閣
  • [Patent(Industrial Property Rights)] 養殖魚用餌及びその製造方法2012

    • Inventor(s)
      潮, 他5名
    • Industrial Property Rights Holder
      双日株式会社
    • Industrial Property Number
      特許出願、特願2012-020944
    • Filing Date
      2012-02-02
  • [Patent(Industrial Property Rights)] 養殖魚死亡抑制剤2012

    • Inventor(s)
      潮, 他4名
    • Industrial Property Rights Holder
      双日株式会社
    • Industrial Property Number
      特許出願、特願2012-020944
    • Filing Date
      2012-02-02
  • [Patent(Industrial Property Rights)] 反芻動物用飼料添加物、及び飼育方法2011

    • Inventor(s)
      潮, 他5名
    • Industrial Property Rights Holder
      東京大学・株式会社サタケ
    • Industrial Property Number
      特許出願、特願2011-140036
    • Filing Date
      2011-07-12
  • [Patent(Industrial Property Rights)] 脂質代謝調節作用を有する食品素材,健康食品,動物用飼料及び動物の飼育方法2011

    • Inventor(s)
      潮, 他4名
    • Industrial Property Rights Holder
      東京海洋大学・株式会社サタケ
    • Industrial Property Number
      特許、特許第4785140号
    • Filing Date
      2011-07-22
  • [Patent(Industrial Property Rights)] 頭足類に属する動物の体色改善剤と頭足類に属する動物の加工方法2011

    • Inventor(s)
      潮, 他3名
    • Industrial Property Rights Holder
      東京海洋大学
    • Industrial Property Number
      特許、特許第4876227号
    • Filing Date
      2011-11-22

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Published: 2013-07-31  

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