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2011 Fiscal Year Final Research Report

Socio-medical research about late-effects among A-bomb survivors

Research Project

  • PDF
Project/Area Number 21249041
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionHiroshima University

Principal Investigator

OHTAKI Megu  広島大学, 原爆放射線医科学研究所, 教授 (20110463)

Co-Investigator(Kenkyū-buntansha) KAWANO Noriyuki  広島大学, 平和科学研究センター, 准教授 (30304463)
KAWAKAMI Hideji  広島大学, 原爆放射線医科学研究所, 教授 (70253060)
KIMURA Akirou  広島大学, 原爆放射線医科学研究所, 授教 (70127645)
HOSHI Masaharu  広島大学, 原爆放射線医科学研究所, 教授 (50099090)
KOIKE Seiichi  広島大学, 大学院・国際協力研究科, 教授 (70274024)
NUNOKAWA Hiroshi  広島大学, 大学院・総合科学研究科, 教授 (30294474)
ENDO Satoru  広島大学, 大学院・工学研究院, 准教授 (90243609)
HARADA Yuka  広島大学, 原爆放射線医科学研究所, 助教 (50379848)
Co-Investigator(Renkei-kenkyūsha) SATOH Kenichi  広島大学, 原爆放射線医科学研究所, 准教授 (30284219)
TONDA Tetsuji  広島大学, 原爆放射線医科学研究所, 助教 (60346533)
Project Period (FY) 2009 – 2011
Keywords原爆被爆者 / 放射線障害 / コホート研究 / アンケート調査 / がん死亡危険度
Research Abstract

The geographical distribution of mortality risk due to solid tumors among A-bomb survivors in Hiroshima was statistically estimated through a cohort analysis. The resultant contour map suggests that the region west to the hypocenter has a higher risk compared to other areas, which suggested the effect of additional exposure due to black rain. Relationship between damage situations due to A-bomb and degree of anxiety about their own health or their offspring were analyzed statistically. A gene that was found with specifically high frequency among MDS patients living near Semipalatinsk nuclear test site and A-bomb survivors was identified. In order to evaluate indirect dose of radiation among A-bomb survivors, dose ofβ-ray due to radiation fallout was estimated.

  • Research Products

    (26 results)

All 2012 2011 2010 2009

All Journal Article (14 results) (of which Peer Reviewed: 12 results) Presentation (10 results) Book (2 results)

  • [Journal Article] Investigation oncircular asymmetry of geographicald is tribution in cancer mortality of Hiroshima atomic bomb survivorsbased on risk maps2012

    • Author(s)
      Tonda T, Satoh K, Otani K, Sato Y, Maruyama H, Kawakami H, Tashiro S, Hoshi M, Ohtaki M
    • Journal Title

      analysis of spatial survival data, Radiat Environ Biophys

    • Peer Reviewed
  • [Journal Article] Expansion of CD8+/ perforin+ T-cells predicts response to ciclosporinA therapy in patients with erythroidhypoplasia/ aplasia2012

    • Author(s)
      Nitta H, Harada Y, Hyodo H, Kimura A, Harada H
    • Journal Title

      Brit. J. Haemtol

    • Peer Reviewed
  • [Journal Article] Radiation exposure and disease ques tionnaires of earlye ntrants after the Hiro shima Bombing2012

    • Author(s)
      Imanaka T, Endo S, Kawano N, Tanaka K
    • Journal Title

      Radiation Protection Dosimetry

      Volume: 149 Pages: 91-96

    • Peer Reviewed
  • [Journal Article] Anonparametric mixed-effects model forcancer mortality2011

    • Author(s)
      Tonda T, Satoh K, Nakayama T, Katanoda K, Sobue T and Ohtaki M
    • Journal Title

      Aust. N. Z. J. Stat

      Volume: 53 Pages: 247-256

    • Peer Reviewed
  • [Journal Article] Re-construction of spatial-time distribution of black rainin Hiroshima based on statisticalanalysis of witness of survivors from atomic bomb, Revisit The HiroshimaA-bomb with a Database-LatestScientific View on Local Fallout andBlack Rain-2011

    • Author(s)
      Ohtaki M
    • Journal Title

      Hiroshima City

      Pages: 131-144

    • Peer Reviewed
  • [Journal Article] Effect of mustardgas exposure on incidence of lungcancer2011

    • Author(s)
      Doi M, Hattori N, Yokoyama A, OnariY, Kanehara M, Masuda K, Tonda T, Ohtaki M, Kohno N
    • Journal Title

      a longitudinal study, Am JEpidemiol

      Volume: 173 Pages: 659-666

    • Peer Reviewed
  • [Journal Article] 教育講演5:放射線障害としての血液疾患骨髄異形成症候群・白血病を中心に2011

    • Author(s)
      木村昭郎
    • Journal Title

      「第108回日本内科学会講演会教育講演」.日本内科学会雑誌

      Volume: 100(9) Pages: 2612-2618

    • Peer Reviewed
  • [Journal Article] Mole cularmechanisms that produce secondaryMDS/ AML by RUNX1/ AML1 pointmutations2011

    • Author(s)
      Harada Y, Harada H
    • Journal Title

      J Cell Biochem

      Volume: 112 Pages: 425-432

    • Peer Reviewed
  • [Journal Article] Estimation of beta-ray skin dose from exposure tofission fallout from the Hiroshimaa to mic bomb2011

    • Author(s)
      Endo S, Tanaka K, Shizuma K, Hoshi M, Imanaka T
    • Journal Title

      Radiation Protection Dosimetry

    • DOI

      doi:10.1093/rpd/ncr407,pp1-7.

    • Peer Reviewed
  • [Journal Article] Radiation exposure anddisease questionnaires of earlyentrants after the Hiroshima bombing2011

    • Author(s)
      Imanaka T, Endo S, Kawano N, Tanaka K
    • Journal Title

      Radiation Protection Dosimetry

    • DOI

      doi:10.1093/rpd/ncr370,pp.1.6.

    • Peer Reviewed
  • [Journal Article] 地図情報システムを用いた被爆者位置情報の高精度化の試み2010

    • Author(s)
      佐藤裕哉, 星正治, 大瀧慈, 丸山博文, Harry M Cullings, 川上秀史
    • Journal Title

      広島医学

      Volume: 64(4) Pages: 264-264

    • Peer Reviewed
  • [Journal Article] 原爆被爆者は何を伝えたいのか-原爆被爆者の体験記・メッセージの計量解析を通して-2010

    • Author(s)
      川野徳幸, 佐藤健一, 大瀧慈
    • Journal Title

      長崎医学会雑誌

      Volume: 85 Pages: 208-213

  • [Journal Article] 原爆被爆者の不安度における被爆状況依存性について.朝日新聞社アンケート調査に基づく解析.2010

    • Author(s)
      川野徳幸, 大谷敬子, 佐藤健一, 冨田哲治, 大瀧慈
    • Journal Title

      広島医学

      Volume: 広島医学, Pages: 270-274

    • Peer Reviewed
  • [Journal Article] 広島の復興と広島平和記念都市法2010

    • Author(s)
      布川弘
    • Journal Title

      芸備地方史研究

      Volume: 272号 Pages: 2-5

  • [Presentation] Outline of database of atomic bomb survivors in Hiroshima prefecture(ABS) and toward practice2012

    • Author(s)
      Sato Y, Hara N, Hiraoka M, Tonda T, Maruyama H, Kawakami H, Hoshi M, Tashiro S, Ohtaki M
    • Organizer
      International Symposium 50^th Anniversary of RIRBM
    • Place of Presentation
      Hiroshima University, Hiroshima
    • Year and Date
      2012-02-21
  • [Presentation] Defeat and'the City ofthe Dead-In View of BCOF PersonnelOccupying Kure and Hiroshima-'2011

    • Author(s)
      Nunokawa H
    • Organizer
      Inter national Sym posium on the Naval Port, no proceeding
    • Place of Presentation
      Gyeongnam Development Institute, Korea
    • Year and Date
      2011-08-25
  • [Presentation] Evaluation of effects of Atomic bombsurvivors' health hand book on their health promotion2011

    • Author(s)
      Otani K, Ohtaki M, Tonda T, Satoh K
    • Organizer
      World Congress of Epidemiology
    • Place of Presentation
      Edinburgh, Scotland
    • Year and Date
      2011-08-09
  • [Presentation] Cancermortality risk visualization on theage-period space by regression models2011

    • Author(s)
      Satoh K, Kamo K and Tonda T
    • Organizer
      World Congress of Epidemiology 2011
    • Place of Presentation
      Edinburgh, Scotland
    • Year and Date
      2011-08-09
  • [Presentation] Statisticalanalysis for spatial survival data and its application to cohort study of Hiroshima atomic bomb survivors2011

    • Author(s)
      Tonda T, Satoh K, Otani K, Sato Y, Maruyama H, Kawakami H, Tashiro S, Hoshi M, Ohtaki M
    • Organizer
      World Congress of Epidemiology 2011
    • Place of Presentation
      Edinburgh, Scotland
    • Year and Date
      2011-08-09
  • [Presentation] 被爆者健康手帳の取得期間と死亡リスクに関する統計解析2011

    • Author(s)
      大谷敬子, 大瀧慈, 佐藤健一, 冨田哲治
    • Organizer
      2011年度日本計量生物学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2011-05-25
  • [Presentation] Estimation of Beta-ray Skin Dose from Fission Fallout. RERF International Workshop on Potential Improvements to Organ Dose Calculation for the Atomic Bomb Survivors Using DS02 Fluences2011

    • Author(s)
      Endo S
    • Organizer
      Radiation Effects Research Foundation
    • Place of Presentation
      Hiroshima, Japan
    • Year and Date
      2011-03-07
  • [Presentation] アンケート調査により推定された広島の黒い雨の時空間分布について,シンポジュウム「広島"黒い雨"地域におけるローカル・フォールアウトの実態解明」2010

    • Author(s)
      大瀧慈
    • Organizer
      第53回日本放射線影響学会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-22
  • [Presentation] 原爆被爆者の健康不安に関する解析2010

    • Author(s)
      大谷敬子, 大瀧慈, 佐藤健一, 川野徳幸
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-21
  • [Presentation] An Outline of A-Bomb Damages and Mental Effects/ Social discriminations on the Residents in Hiroshima and Nagasaki2009

    • Author(s)
      Kawano N
    • Organizer
      Int. WS on Chernobyl Health Consequences
    • Place of Presentation
      Kiev Ukraine
    • Year and Date
      2009-11-30
  • [Book] 『チェルノブイリ・旧プリピャチ住民へのインタビュー記録2012

    • Author(s)
      川野徳幸,今中哲二:竹内高明編
    • Total Pages
      184
    • Publisher
      広島大学平和科学研究センター, 2012
  • [Book] 血液専門医テキスト, 骨髄性白血病の発症機構.I章.造血システムと腫瘍化(日本血液学会編)2011

    • Author(s)
      原田結花,原田浩徳
    • Total Pages
      566

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Published: 2013-07-31  

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