International Comparison of Emission, Transport, Secondary Formation and Exposure of Toxic Polycyclic Aromatic Hydrocarbons in Pan-Japan Sea Region

2013 Fiscal Year Final Research Report

• Project/Area Number: 21256001
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Environmental pharmacy
• Research Institution: Kanazawa University
• Principal Investigator: HAYAKAWA Kazuichi 金沢大学, 薬学系, 教授 (40115267)
• Co-Investigator(Kenkyū-buntansha): TORIBA Akira 金沢大学, 薬学系, 准教授 (50313680) ; KAMEDA Takayuki 京都大学, 大学院・エネルギ-科学研究科, 准教授 (50398426) ; TANG Ning 金沢大学, 薬学系, 助教 (90372490)
• Project Period (FY): 2009-04-01 – 2014-03-31
• Keywords: 日本海域 / 多環芳香族炭化水素 / 発生源 / 長距離輸送 / 曝露 / ニトロ多環芳香族炭化水素 / 分析法 / 長距離輸送

Research Abstract

East Asian countries surrounding Japan Sea, such as Japan, China, Korea and Russia, have shown significant change of atmospheric conditions with fast industrial development. Atmospheric behaviors of carcinogenic polycyclic aromatic hydrocarbon (PAH) and nitropolycyclic aromatic hydrocarbon (NPAH) were studied in this area. Their atmospheric concentrations decreased in Japanese cities by the effective countermeasures against automobile exhaust. However, several cities in China and Russia showed the increasing tendency of the concentrations. By using the analytical results, the emission inventory and the chemical transport model were newly developed. In the atmosphere, on the other hand, several oxidized derivatives of PAHs and NPAHs formed through secondary formation were identified. Several compound of metabolites and secondary formed derivatives of PAHs and NPAHs showed strong biological activities such as mutagenicity and endocrine disruption.

Research Products

• [Journal Article] Characterization and functionality of immidazolium ionic liquids modified magnetic nanoparticles (2013)
  • Author(s): Li, Y., Tang, N., Inagaki, F., Mukai, C., Hayakawa, K
  • Journal Title: J. Chem Volume: 861021 Pages: 7
  • DOI: 10.1155/2013/861021
  • Peer Reviewed
• [Journal Article] Determination of selected nitropolycyclic aromatic hydrocarbons in waters samples (2013)
  • Author(s): Chondo, Y., Ying, Li., Makino, F., Tang, N., Toriba, A., Kameda, T., Hayakawa, K
  • Journal Title: Chem. Pharm. Bull Volume: 61(12) Pages: 1269-1274
  • DOI: 10.1248/cpb.c13-00547
  • Peer Reviewed
• [Journal Article] Source contribution analysis of surface particulate polycyclic aromatichydrocarbon concentrations in Northeastern Asia by sourceereceptor relationships (2013)
  • Author(s): Inomata, Y., Kajino, M., Sato, K., Ohara, T., Kurokawa, J., Ueda, H., Tang, N., Hayakawa, K., Akimoto, H
  • Journal Title: Environ. Pollut Volume: 182 Pages: 324-334
  • DOI: 10.1016/j.envpol.2013.07.020
  • Peer Reviewed
• [Journal Article] 中国の瀋陽, 上海及び福州のおける大気中多環芳香族炭化水素類の地域間差 (2013)
  • Author(s): 唐 寧, 伊崎陽彦, 徳田貴裕, 季 若男, 薫 麗君, 呉 慶, 周 志俊, 黄 蓉, 林振宇, 亀田貴之, 鳥羽 陽,島 正之, 早川和一
  • Journal Title: 分析化学 Volume: 62(4) Pages: 267-273
  • DOI: 10.2116/bunsekikagaku.62.267
  • Peer Reviewed
• [Journal Article] Distribution of PAHs in the northwestern part of the Japan Sea (2013)
  • Author(s): Chizhova, T., Hayakawa, K., Tischenko, P. Nakase, H., Koudryashova,Yu
  • Journal Title: Deep-Sea Research II Volume: 86-87 Pages: 19-24
  • DOI: 10.1016/j.dsr2.2012.07.042
  • Peer Reviewed
• [Journal Article] Evaluation of urinary metabolites of 1-nitropyrene as biomarkers for exposure to diesel exhaust in taxi drivers of Shenyang, China (2013)
  • Author(s): Miller-Schulze, JP., Paulsen, M., Kameda, T., Toriba, A., Tang, N., Tamura, K., Dong, L., Zhang, X., Hayakawa, K., Yost, MG., Simpson, CD
  • Journal Title: J. Expo Sci. Environ. Epidemiol Volume: 23(2) Pages: 170-175
  • DOI: 10.1038/jes.2012.40
  • Peer Reviewed
• [Journal Article] Polycyclic atmospheric polycyclic hydrocarbons and nitropolycyclic aromatic hydrocarnons in particulates emitted by motorcycles (2013)
  • Author(s): Pham, C. T., Kameda, T., Toriba, A., Hayakawa, K
  • Journal Title: Envion. Pollutiton Volume: 183(1) Pages: 175-183
  • DOI: 10.1016/j.envpol.2013.01.003
  • Peer Reviewed
• [Journal Article] Characteristics of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarnons in Hanoi-Vietnam, as a typical motorbike city (2012)
  • Author(s): Pham, C. T., Kameda, T., Toriba A., Tang, N., Hayakawa, K
  • Journal Title: Polycycl. Aromat. Comp Volume: 32(2) Pages: 296-312
  • DOI: 10.1080/10406638.2012.679015
  • Peer Reviewed
• [Journal Article] Atmospheric formation of hydroxynitrofluoranthene from photochemical reactions of 2-nitrofluoranthene (2012)
  • Author(s): Kameda, T., Akiyama, A., Toriba, A., Tang, N., Hayakawa, K
  • Journal Title: Polycycl. Aromat. Comp Volume: 32 Pages: 177-187
  • DOI: 10.1080/10406638.2011.654307
  • Peer Reviewed
• [Journal Article] Emission and transport of particulate PAHs in Northeast Asia (2012)
  • Author(s): Inomata, Y., Kajino, M., Sato, K., Ohara, T., Kurokawa, J., Ueda, H., Tang, N., Hayakawa, K., Ohizumi, T., Akimoto, H
  • Journal Title: Environ. Sci. Technol Volume: 46(9) Pages: 4941-4949
  • DOI: 10.1021/es300391w
  • Peer Reviewed
• [Journal Article] Determination of benzo[a]pyrene-7, 10-quinone in airborne particulates by using a chemiluminescence reaction of hydrogen peroxide and hydrosulfite (2012)
  • Author(s): Li, R., Kameda, T., Toriba, A., Hayakawa. K., Lin, J.-M
  • Journal Title: Anal. Chem Volume: 84(7) Pages: 3215-3221
  • DOI: 10.1021/ac2032063
  • Peer Reviewed
• [Journal Article] 金沢市内における大気粉塵中多環芳香族炭化水素類およびニトロ多環芳香族炭化水素類の最近12年間の変遷 (2012)
  • Author(s): 濵 寛貴, 徳田貴裕, 伊崎陽彦, 大野友子, 渡辺有梨, 神田哲雄, 唐 寧, 亀田貴之, 鳥羽 陽, 早川和一
  • Journal Title: 大気環境学会誌 Volume: 47(1) Pages: 1-8
  • URL: https://www.jstage.jst.go.jp/article/taiki/47/1/47_1/_pdf
  • Peer Reviewed
• [Journal Article] Recent change in atmospheric polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic aromatic hydrocarbons (NPAHs) in Shenyang, China (2011)
  • Author(s): Tang, N., Tokuda, T., Izzaki, A., Tamura, K., Ji, R., Zhang, X., Dong, L., Kameda, T., Toriba, A., Hayakawa, K
  • Journal Title: Environ. Forensics Volume: 12 Pages: 342-348
  • DOI: 10.1080/15275922.2011.622347
  • Peer Reviewed
• [Journal Article] Development of HPLC determination method for trace levels of 1-, 2-Nitropyrenes and 2-Nitrofluoranthene in airborne particulates and its application to samples collected at Noto peninsula (2011)
  • Author(s): Hayakawa, K., Tang, N., Sato, K., Izaki, A., Tatematsu, M., Hama, H., Li, Y., Kameda, T., Toriba, A
  • Journal Title: Asian J. Atmos. Environ Volume: 5(3) Pages: 146-151
  • URL: http://asianjae.org/browse_sub.html?class_no2=24
  • Peer Reviewed
• [Journal Article] Mutagenicities and endocrine-disrupting activities of 1-hydroxy-2-nitropyrene and 1-hydroxy-5-nitropyrene (2011)
  • Author(s): Kameda, T., Akiyama, A., Yoshita, M., Tachikawa, C., Toriba, A., Tang, N., Hayakawa, K
  • Journal Title: J. Health Sci Volume: 57(4) Pages: 372-377
  • DOI: 10.1248/jhs.57.372
  • Peer Reviewed
• [Journal Article] Estrogenic/antiestrogenic activities of quinoid polycyclic aromatic hydrocarbons (2011)
  • Author(s): Hayakawa, K., Bekki, K., Yoshita, M., Tachikawa, C., Kameda, T., Tang, N., Toriba, A., Hosoi, S
  • Journal Title: J. Health Sci Volume: 57(3) Pages: 274-280
  • DOI: 10.1248/jhs.57.274
  • Peer Reviewed
• [Journal Article] Atmospheric formation of hydroxynitropyrenes from a photochemical reaction of particle-associated 1-nitropyrene (2011)
  • Author(s): Kameda, T., Akiyama, A., Toriba, A., Tang, N., Hayakawa, K
  • Journal Title: Environ. Sci. Technol Volume: 45(8) Pages: 3325-3332
  • DOI: 10.1021/es1042172
  • Peer Reviewed
• [Journal Article] 中国・北京及び日本・金沢の大気が示すAhR 活性化作用へのPAH 類及びダイオキシン類の寄与 (2011)
  • Author(s): 戸次加奈江, 滝上英孝, 鈴木 剛, 唐 寧, 鳥羽 陽, 亀田貴之, 早川和一
  • Journal Title: 環境化学 Volume: 21(1) Pages: 27-33
  • URL: http://www.j-ec.or.jp/publication/journal/vol21.html
  • Peer Reviewed
• [Journal Article] 日本および中国における大気粒子中多環芳香族炭化水素キノンの観測-濃度レベルの把握と発生要因の検討- (2011)
  • Author(s): 片山裕規, 後藤知子, 亀田貴之, 唐 寧, 松木 篤, 鳥羽 陽, 早川和一
  • Journal Title: 大気環境学会誌 Volume: 46(1) Pages: 20-29
  • DOI: 10.11298/taiki.46.20
  • Peer Reviewed
• [Journal Article] Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons (2010)
  • Author(s): Yang, X.-Y., Igarashi, K., Tang, N., Lin, J.-M., Wang, W., Kameda, T., Toriba, A., Hayakawa, K
  • Journal Title: Mutation Res Volume: 695(1-2) Pages: 29-34
  • DOI: 10.1016/j.mrgentox.2009.10.010
  • Peer Reviewed
• [Journal Article] Exposures to particulate air pollution and nitro-polycyclic aromatic hydrocarbons among taxi drivers in Shenyang, China (2010)
  • Author(s): Miller-Schlze, J. P., Toriba, A., Tang, N., Hayakawa, K., Tamura, K., Dong, L., Simpson, C. D
  • Journal Title: Environ. Sci. Technol Volume: 44(1) Pages: 216-221
  • DOI: 10.1021/es802392u
  • Peer Reviewed
• [Journal Article] Distribution and source of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in Tieling city, Liaoning province, a typical local city in northeast China (2009)
  • Author(s): Tang, N., Araki, Y., Tamura, K., Dong, L., Zhang, X., Lu, Q., Ji, R., Kameda, T., Toriba. A., Hayakawa, K
  • Journal Title: Asian J. Atmos. Environ Volume: 3(1) Pages: 52-58
  • DOI: 10.5572/ajae.2009.3.1.052
  • Peer Reviewed
• [Journal Article] Determination of airborne particle-associated benz[a]anthracene-7, 12-quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection (2009)
  • Author(s): Kameda, T., Goto, T., Toriba, A., Tang, N., Hayakawa, K
  • Journal Title: J. Chromatogr. A Volume: 1216(39) Pages: 6758-6761
  • DOI: 10.1016/j.chroma.2009.08.009
  • Peer Reviewed
• [Journal Article] Long-range transport of fluoride in East Asia monitored at Noto Penninsula, Japan (2009)
  • Author(s): Yang, X.-Y., Yamada, M., Tang, N., Lin, J.-M., Wang, W., Kameda, T., Toriba, A., Hayakawa, K
  • Journal Title: Sci. Total Environ Volume: 407(16) Pages: 4681-4686
  • DOI: 10.1016/j.scitotenv.2009.05.005
  • Peer Reviewed
• [Journal Article] Determination of 1-nitropyrene in low volume anbient air samples by high-performance liquid chromatography with fluorescence detection (2009)
  • Author(s): Ohno, T., Toriba, A., Kameda, T., Tang, N., Hayakawa, K
  • Journal Title: J. Chromatogr. A Volume: 1216(21) Pages: 4625-4628
  • DOI: 10.1016/j.chroma.2009.03.070
  • Peer Reviewed
• [Journal Article] Polycyclic aromatichydrocarbons and nitropolycyclic aromatic hydrocarnons in soil and atmospheric particles at a traffic site in Hanoi, Vietnam
  • Author(s): Pham, C. T., Tang, N., Toriba A., Hayakawa, K
  • Journal Title: Polycycl. Aromat. Comp Volume: (in press)
  • Peer Reviewed
• [Journal Article] Factors affecting atmospheric 1-, 2-nitropyrenes and 2-nitrofluoranthene in winter at Noto peninsula, a remote background site, Japan
  • Author(s): Tang, N., Sato, K., Tokuda, T., Tatematsu, M., Hama, H., Suematsu, T., Kameda, T., Toriba, A., Hayakawa, K
  • Journal Title: Chemosphere Volume: (in press)
  • Peer Reviewed
• [Presentation] Influence of biomass burning on the levels of atmospheric polycyclic aromatic hydrocarbons and their nitrated derivatives in Chiang Mai, Thailand (2012)
  • Author(s): Chuesaard, T
  • Organizer: 2nd Annual meeting of the international society of exposure science (ISES2012)
  • Place of Presentation: Westin Seattle
  • Year and Date: 20121028-1102
• [Presentation] Newly developed emission inventory, REAS-POP : particulate PAHs in Northeast Asia (2012)
  • Author(s): Inomata, Y
  • Organizer: Third international workshop on emission Inventory in Asia
  • Place of Presentation: 三好記念ホール
  • Year and Date: 20120224-25
• [Presentation] Change of air pollution in Japan during last 14 years from view point of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons (2011)
  • Author(s): Hayakawa, K
  • Organizer: The 14th Beijing Conference and Exhibition on Instrumental Analysis (BCEIA2011)
  • Place of Presentation: Beijing Exhibition Center
  • Year and Date: 20111012-15
• [Presentation] Atmospheric formation of hydroxynitrofluoranthene from a photochemical reaction of particle-associated 2-nitrofluoranthene (2011)
  • Author(s): Kameda, T
  • Organizer: 23rd International Symposium on Polycyclic Aromatic Compounds (ISPAC 23)
  • Place of Presentation: University of Munster
  • Year and Date: 20110904-08
• [Presentation] Change of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in last 12 years of Kanazawa (2011)
  • Author(s): Hayakawa, K
  • Organizer: International Network of Environmental Forensics (INEF) Conference
  • Place of Presentation: St John's College
  • Year and Date: 20110724-27
• [Presentation] Determination of atmospheric polycyclic aromatic hydrocarbons/nitropolycyclic aromatic hydrocarbons in East Asia and its long-range transport to Japan (2011)
  • Author(s): Hayakawa, K
  • Organizer: IUPAC International Congress on Analytical Sciences 2011 (ICAS2011)
  • Place of Presentation: Kyoto International Conference Center
  • Year and Date: 20110522-26
• [Presentation] Polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in urban air particulates of Hanoi capital - Vietnam (2011)
  • Author(s): Pham, C. T
  • Organizer: The 52nd Meeting of Korean Society for Atmospheric Environment (2011)
  • Place of Presentation: National Institute of Environmental Research
  • Year and Date: 20110512-14
• [Presentation] Atmospheric pollution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in East Asia (2010)
  • Author(s): Hayakawa, K
  • Organizer: 2010 International Chemical Congress of Pacific Basin Societies
  • Place of Presentation: Hawaii Convention Center
  • Year and Date: 20101215-20
• [Presentation] Behaviors of polycyclic aromatic hydrocarbons in East Asia (2010)
  • Author(s): Hayakawa, K
  • Organizer: The 4th International Symposium on Environment of Rim of the Japan/East Sea. The 4th International Symposium on Environment of Rim of the Japan/East Sea
  • Place of Presentation: Seogwipo KAL Hotel
  • Year and Date: 20101018-19
• [Presentation] Polycyclic aromatic hydrocarbons and metabolites : determination methods, atmospheric behavior and human exposure in East Asia (2009)
  • Author(s): Hayakawa, K
  • Organizer: BCEIA 2009
  • Place of Presentation: Beijing Exhibition Center
  • Year and Date: 20091125-28
• [Presentation] Recent change in contributiors to atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in Shenyang. China (2009)
  • Author(s): Tang, N
  • Organizer: International Network of Environmental Forensics Conference 2009 in Calgary
  • Place of Presentation: California Polytechnic State University
  • Year and Date: 20090830-31