2011 Fiscal Year Final Research Report
Neuroimaging and Neuropsychological studies on neural basis of episodic memory
| Project/Area Number |
21300101
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cognitive science
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| Research Institution | Tohoku University |
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Principal Investigator |
FUJII Toshikatsu 東北大学, 大学院・医学系研究科, 准教授 (70271913)
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| Co-Investigator(Renkei-kenkyūsha) |
ABE Nobuhito 東北大学, 大学院・医学系研究科, 助教 (90507922)
MUGIKURA Shunji 東北大学, 大学病院, 助教 (20375017)
MORI Etsuro 東北大学, 大学院・医学系研究科, 教授 (30368477)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 脳認知科学 / エピソード記憶 / 文脈記憶 / 内側側頭葉 / 前頭前野 |
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| Research Abstract |
The functions of various brain areas on the encoding and retrieval of episodic memory have been studied intensely, yet the specific contribution of each brain area has not been elucidated. The purpose of the present study was to identify neural networks that support event memory itself, temporal context memory, spatial context memory, and source memory. For this purpose, we employed both neuroimaging and neuropsychological studies. The results showed (1)the influence of prefrontal activity on medial temporal lobe activity during the retrieval of episodic memory,(2)the crucial role of the medial temporal lobe in the retrieval of source memory, and (3)the differential roles of subregions within the medial temporal lobe in episodic memory.
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[Journal Article] The effects of aging and Alzheimer's disease on associative recognition memory2011
Author(s)
Hanaki R, Abe N, Fujii T, Ueno A, Nishio Y, Hiraoka, K Shimomura T, Iizuka O, Shinohara M, Hirayama K, Mori E.
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Journal Title
Neurological Sciences
Volume: 32
Pages: 1115-1122
Peer Reviewed
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[Journal Article] False item recognition in patients with Alzheimer's disease2011
Author(s)
Abe N, Fujii T, Nishio Y, Iizuka O, Kanno S, Kikuchi H, Takagi M, Hiraoka K, Yamasaki H, Choi H, Hirayama K, Shinohara M, Mori E.
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Journal Title
Neuropsychologia
Volume: 49
Pages: 1897-1902
Peer Reviewed
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[Journal Article] Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behavior2009
Author(s)
Abe N, Fujii T, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Nishio Y, Suzuki K, Itoyama Y, Takahashi S, Fukuda H, Mori E.
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Journal Title
Brain
Volume: 132
Pages: 1386-1395
Peer Reviewed
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[Journal Article] Quantitative analysis of donepezil binding to acetylcholinesterase using positron emission tomography and [5-(11)C-methoxy] donepezil2009
Author(s)
Hiraoka K, Okamura N, Funaki Y, Watanuki S, Tashiro M, Kato M, Hayashi A, Hosokai Y, Yamasaki H, Fujii T, Mori E, Yanai K, Watabe H.
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Journal Title
Neuroimage
Volume: 46
Pages: 616-623
Peer Reviewed
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[Presentation] Dissociating areas for novelty detection and for episodic encoding within the human medial temporal lobe2011
Author(s)
Koseki Y, Ito A, Abe N, Ueno A, Hayashi A, Mori E, Sung Y, Matsue Y, Fujii T.
Organizer
International Neuropsychological Society, 39th Annual Meeting
Place of Presentation
Boston, USA
Year and Date
20110202-05
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[Presentation] The role of dorsolateral prefrontal cortex in deception for emotional and neutral events2011
Author(s)
Ito A, Abe N, Fujii T, Ueno A, Koseki Y, Hashimoto R, Mugikura S, Takahashi S, Mori E.
Organizer
International Neuropsychological Society, 39th Annual Meeting
Place of Presentation
Boston, USA
Year and Date
20110202-05
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[Presentation] Neural correlates of moral judgment about anti-and pro-social lying2011
Author(s)
Hayashi A, Abe N, Fujii T, Ito A, Ueno A, Koseki Y, Mugikura S, Takahashi S, Mori E.
Organizer
International Neuropsychological Society, 39th Annual Meeting
Place of Presentation
Boston, USA
Year and Date
20110202-05
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