2011 Fiscal Year Final Research Report
Neural mechanisms in early visual information processing
| Project/Area Number |
21300148
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TACHIBANA Masao 東京大学, 大学院・人文社会系研究科, 教授 (60132734)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 神経科学 / 生理学 / 脳・神経 / シグナル伝達 / 視覚 / 網膜 / 電気シナプス / 抑制性シナプス |
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| Research Abstract |
We examined the visual information processing in the retina. Bipolar cells, the second order neurons, were electrically coupled with each other through gap junctions at their dendrites. At the axon terminal these cells received reciprocal inhibitory inputs and wide-field lateral inhibitory inputs from amacrine cells. Both inputs were GABAergic but their synaptic properties were different. Excitation of electrically-coupled multiple bipolar cells was essential for the activation of lateral inhibition.
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