2011 Fiscal Year Final Research Report
The development of image-guided and electrophysiological navigation for deep brain stimulation surgery
| Project/Area Number |
21300188
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Nagoya University |
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Principal Investigator |
YASUKAZU Kajita 名古屋大学, 大学院・医学系研究科, 准教授 (70303617)
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| Co-Investigator(Kenkyū-buntansha) |
MORI Kensaku 名古屋大学, 情報連携統括本部, 教授 (10293664)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 脳深部刺激術 / パーキンソン病 / ナビゲーション / 3D手術支援画像 |
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| Research Abstract |
Deep brain stimulation(DBS) of the subthalamic nucleus(STN) for the patients with Parkinson disease(PD) is performed using intraoperative microelectrode recording(MER) to define the optimal site. The correlation between microelectrode criteria and surgical outcome was respectively examined in the patients with STN DBS. The number of total STN neurons, movement-related neurons and the length of STN recorded were significantly correlated with improvement of the surgical outcome and the number of movement-related neurons was most strongly related with the surgical outcome. We developed the new image analysis technique based on non-linear transformation theory. The brain shift is evaluated according to the volume of free air in the skull X-P(front and lateral view) taken intraoperatively, resulting calculation of AC and PC displacement. Totally, we developed the electrophysiological navigation of which the single unit recording data significantly correlated to the surgical outcome is considered and the real-time electrophysiological data can be fitted to the 3Dvirtual Schaltenbland and Wahren atlas
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[Journal Article] Neurosurgical robotic system for brain tumor removal2010
Author(s)
Jumpei Arata, Yasunori Tada, Hiroaki Kozuka, Tomohiro Wada, Yoshitaka Saito, Norio Ikedo, Yuichiro Hayashi, Masazumi Fujii, Yasukazu Kajita, Masaaki Mizuno, Toshihiko Wakabayashi, Jun Yoshida and Hideo Fujimoto
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Journal Title
Int. J. of Computer Assisted Radiology and Surgery
Volume: Vol.6, No.3
Pages: 375-385
Peer Reviewed
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[Journal Article] 軟性神経内視鏡手術ナビゲーションにおける仮想内視鏡視軸と実内視鏡視軸回転誤差の簡便な補正手法2010
Author(s)
蒋振剛, 二村幸孝, 北坂孝幸, 林雄一郎, 伊藤英治, 藤井正純, 永谷哲也, 梶田泰一, 若林俊彦, 森健策
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Journal Title
日本コンピュータ外科学会論文誌
Volume: Vol.12, No.2
Pages: 65-77
Peer Reviewed
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[Journal Article] A new flexible neuroendoscopic surgery navigation system using electromagnetic tracker2009
Author(s)
Zhengang Jiang, Kensaku Mori, Yukitaka Nimura, Yasuhito Suenaga, Takayuki Kitasaka, Hayashi Yuichiro, Eiji Ito, Masazumi Fujii, Tetsuya Nagatani, Yasukazu Kajita and Toshihiko Wakabashi
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Journal Title
Int. J. of Computer Assisted Radiology and Surgery
Volume: Vol.4, Suppl. 1
Pages: 248-249
Peer Reviewed
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