2011 Fiscal Year Final Research Report
Molecular biological study of Muscle metabolic marker on muscle strengthening and disuse weakness
| Project/Area Number |
21300201
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
IKEDA Satoshi 鹿児島大学, 医学部・歯学部附属病院, 講師 (00343369)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Akira 鹿児島大学, 医歯学総合研究科, 助教 (40347109)
KAMIKAWA Yurie 鹿児島大学, 医学部・歯学部附属病院, 医員 (70418804)
OOWATASHI Akihiko 鹿児島大学, 医学部, 助教 (30295282)
KAWAHIRA Kazumi 鹿児島大学, 医歯学総合研究科, 教授 (20117493)
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| Project Period (FY) |
2009 – 2011
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| Keywords | リハビリテーション医学 / 廃用性筋力低下 / 筋力増強 / 分子生物学 / Myogenin / MyoD / 動物モデル / myostatin |
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| Research Abstract |
Muscle strengthening and disuse weakness are very important on rehabilitation medicine. However, there are little study about muscle strengthening from the view point of molecular biology. Then, we examined the gene expression of muscular transcription factors, muscular growth factor, muscle constriction protein by real time RT-PCR method. Besides, quantitative analysis of myostatin on denervation model were done.
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