2011 Fiscal Year Final Research Report
Screening of foods with anti-diabetic-complications function and elucidation of their functionality and mechanism of the function
| Project/Area Number |
21300278
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Kochi University |
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Principal Investigator |
YAGI Toshiharu 高知大学, 教育研究部・自然科学系, 教授 (90110759)
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| Co-Investigator(Kenkyū-buntansha) |
TODA Katsumi 高知大学, 教育研究部・医療学系, 准教授 (40197893)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 健康と食生活 |
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| Research Abstract |
Pyridoxamine(PM), one of vitamin B_6, has anti-diabetic-complications function. Foods containing a lot of PM, thus, may have this function. At first, a novel determination method of PM in foods has been developed. PM contents in several foods were determined. Then, PM was supplied to mice, and expression levels of genes encoding gluconeogenesis-related proteins. PM increased gluconeogenesis in the mice.
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Research Products
(18 results)
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[Journal Article] Development of simultaneous enzymatic assay method for all six individual vitamin B_6 forms and pyridoxine-β-glucoside2010
Author(s)
Yagi, T., Murayama, R., Do, H. T. V., Ide, Y., Mugo, A. M., Yoshikane, Y.
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Journal Title
J. Nutr. Sci. Vitaminol
Volume: 56(3)
Pages: 157-163
Peer Reviewed
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[Journal Article] Crystallization and preliminary X-ray analysis of 4-Pyridoxolactonase from Mesorhizobium loti2009
Author(s)
Matsuda, S., Yokochi, N., Yoshikane, Y., Kobayashi, J., Huy, C. N., Baba, S., Kuramitsu, S., (...), Yagi, T.
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Journal Title
Acta Crystal. Sect
Volume: F 65(9)
Pages: 886-889
Peer Reviewed
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[Journal Article] Crystallization and preliminary X-ray analysis of AAMS amidohydrolase, the final enzyme in degradation pathway i of pyridoxine2009
Author(s)
Kobayashi, J., Yoshida, H., Chu, H. N., Yoshikane, Y., Kamitori, S., Yagi, T.
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Journal Title
Acta Crystal. Se
Volume: F 65(8)
Pages: 829-831
Peer Reviewed
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[Journal Article] Gene identification and characterization of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase2009
Author(s)
Yokochi, N., Yoshikane, Y., Matsumoto, S., Fujisawa, M., Ohnishi, K., Yagi, T.
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Journal Title
J. Biochem
Volume: 145(4)
Pages: 493-503
Peer Reviewed
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