2011 Fiscal Year Final Research Report
Control of a small amount of molecules in two-dimensional monolayer by local modification
| Project/Area Number |
21350001
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
MURAKOSHI Kei 北海道大学, 大学院・理学研究院, 教授 (40241301)
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| Co-Investigator(Kenkyū-buntansha) |
NABIKA Hideki 北海道大学, 大学院・理学研究院, 助教 (30372262)
YASUDA Satoshi 北海道大学, 大学院・理学研究院, 講師 (90400639)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 脂質二分子膜 / 蛍光標識脂質分子 / 全反射顕微鏡 / 分子フィルター / ゲート構造 |
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| Research Abstract |
We revealed that molecules with distinct sizes and strictures in self-spreading lipid bilayer are selectively filtered when the bilayer spread through the metallic nanogates. In order to make clear the origin of this molecular filtering phenomenon, we have observed molecular diffusion in nano space by single molecular tracking. In this research, metal nanogates with sizes of 100 nm was fabricated on cover slips with using electron beam lithography. The quantitative evaluation by single molecular tracking can reveal that the structural change of lipid bilayer correlates molecular diffusion change in nano space.
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