2011 Fiscal Year Final Research Report
Chiral Memory Using the Property of Organic Crystals
Project/Area Number |
21350024
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Organic chemistry
|
Research Institution | Chiba University |
Principal Investigator |
SAKAMOTO Masami 千葉大学, 大学院・工学研究科, 教授 (00178576)
|
Project Period (FY) |
2009 – 2011
|
Keywords | 有機光化学 / 有機合成化学 / 不斉合成 / 有機結晶 |
Research Abstract |
New absolute asymmetric synthesis using the property of organic crystals were developed. Crystallization under various conditions was examined and was clarified a change of molecular structure, polymorphism and the crystal structure. Furthermore, I succeeded in controlling the rate of racemization of the apparent chiral molecules in the chiral crystals, and leading it effectively to the optically active products. I also developed the highly diastereoselective reaction using chiral memory controlled by crystallization induced diastereomer transformation (CIDT).
|
Research Products
(56 results)