2011 Fiscal Year Final Research Report
display of synthetic antigens on intestinal bacteria based on chemicalbiology and their applications for mucosal vaccines
| Project/Area Number |
21350090
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemistry related to living body
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| Research Institution | Ochanomizu University |
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Principal Investigator |
SADAMOTO Reiko お茶の水女子大学, お茶大アカデミック・プロダクション, 特任助教 (50372264)
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| Co-Investigator(Kenkyū-buntansha) |
KODA Toshiaki 北海道大学, 先端生命科学研究院, 教授 (20170186)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 乳酸菌 / 大腸菌 / バクテリア細胞壁 / 糖ペプチド |
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| Research Abstract |
The bacterial cell-wall precursor GlcLev-1-P was not displayed on the mammalian cell surface. To confirm the orthogonal properties, bacteria-specific surface display in a co-culture system of intestinal epithelial cells(Caco-2, HT29, LS180) and bacteria is currently underway.
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