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2011 Fiscal Year Final Research Report

Multifunctional and Highly Reliable Ventricular Assist Devices Utilizing Maglev Centrifugal Pump Technology

Research Project

  • PDF
Project/Area Number 21360072
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Design engineering/Machine functional elements/Tribology
Research InstitutionTokyo Institute of Technology

Principal Investigator

SHINSHI Tadahiko  東京工業大学, 精密工学研究所, 教授 (60272720)

Co-Investigator(Renkei-kenkyūsha) TAKATANI Sestuo  東京医科歯科大学, 生体材料工学所, 教授 (40154786)
Project Period (FY) 2009 – 2011
Keywords補助人工心臓 / 磁気軸受 / 遠心血液ポンプ / 小型化 / 多機能化 / 高信頼化
Research Abstract

Implantable Ventricular Assist Devices(VAD) have already been applied to clinical practices in Europe, the United States and Japan. In the near future, the number of VAD implantations is expected to become more than the number of heart transplants. This research is related to implantable centrifugal blood pump systems utilizing magnetic bearing technology, which can achieve high durability and high biocompatibility of the VADs. In this report, the realization of multifunctional, highly reliable and compact VADs, which can estimate the blood flow and the blood viscosity, have backup functions in the case of mechanical and electrical faults, and can be implanted in children's bodies, are discussed.

  • Research Products

    (27 results)

All 2012 2011 2010 2009 Other

All Journal Article (11 results) (of which Peer Reviewed: 10 results) Presentation (9 results) Remarks (1 results) Patent(Industrial Property Rights) (6 results) (of which Overseas: 5 results)

  • [Journal Article] A cost-effective extracorporeal magnetically-levitated centrifugal blood pump employing adisposable magnet-free impeller2011

    • Author(s)
      W Hijikata, T Mamiya, T Shinshi, STakatani
    • Journal Title

      Proc. IMechE, J. Engineering in Medicine

      Volume: Vol.225 Pages: 1149-1157

    • Peer Reviewed
  • [Journal Article] Fault-tolerant strategies for an implantable centrifugal blood pump using a radially controlled magneticbearing2011

    • Author(s)
      Chi Nan Pai, Tadahiko Shinshi
    • Journal Title

      Medical Engineering & Physics

      Volume: 33 Pages: 906-915

    • Peer Reviewed
  • [Journal Article] 小型遠心血液ポンプ用1自由度制御型磁気軸受モータの研究2011

    • Author(s)
      湯本淳史, 上田学, 進士忠彦
    • Journal Title

      日本機械学会論文集,日本機械学会

      Volume: vol.77, no.779 Pages: 257-266

    • Peer Reviewed
  • [Journal Article] 体外循環用磁気浮上使い捨て遠心血液ポンプ2010

    • Author(s)
      土方亘, 進士忠彦, 染谷毅, 荒井裕国, 高谷節雄, 下河邉明
    • Journal Title

      精密工学会誌

      Volume: Vol.76, No.9 Pages: 1064-1069

    • Peer Reviewed
  • [Journal Article] Development of a Disposable Mgnetically Levitated Centrifugal Blood Pump(Med Tech Dispo) Intended for Bridge-to-Bridge Applications Two-Week In Vivo Evaluation2010

    • Author(s)
      Eiki Nagaoka, Takeshi Someya, Takashi Kitao, Taro Kimura, Tomohiro Ushiyama, Wataru Hijikata, Tadahiko Shinshi, Hiroyuki Arai, Setsuo Takatani
    • Journal Title

      Artificial Organs, Artificial Organs

      Volume: Vol.34, No.9 Pages: 778-783

    • Peer Reviewed
  • [Journal Article] Disposable MagLev Centrifugal Blood Pump Utilizing a Cone-Shaped Impeller2010

    • Author(s)
      Wataru Hijikata, Hideo Sobajima, Tadahiko Shinshi, Yasuyuki Nagamine, Suguru Wada, Setsuo Takatani, Akira Shimokohbe
    • Journal Title

      Artif Organs, Artif Organs

      Volume: Vol.34, No.8 Pages: 669-676

    • Peer Reviewed
  • [Journal Article] Estimation of the radial force using adisturbance force observer for amagnetically levitated centrifugal blood pump2010

    • Author(s)
      Chi Nan Pai, T. Shinshi, A. Shimokohbe
    • Journal Title

      J. Engineering in Medicine

      Volume: vol.224 Pages: 913-924

    • Peer Reviewed
  • [Journal Article] Sensorless measurement of pulsatile flow rate using a disturbance force observer in amagnetically levitated centrifugal blood pump during ventricular assistance2010

    • Author(s)
      Chi Nan Pai, Tadahiko Shinshi, Akira Shimokohbe
    • Journal Title

      Flow Measurement andInstrumentation, Elsevier

      Volume: Volume 21, 1 Pages: 33-39

    • Peer Reviewed
  • [Journal Article] Development of a Disposable Mag-Lev Centrifugal Blood Pump(Med Tech Dispo) Intended for One Month Support in Bridge-to-Bridge Applications-InVitro and Initial In Vivo Evaluations2009

    • Author(s)
      Takeshi Someya, Mariko Kobayashi, Satoshi Waguri, Tomohiro Ushiyama, Eiki Nagaoka, Wataru Hijikata, Tadahiko Shinshi, Hirokuni Arai, Setsuo Takatani
    • Journal Title

      Artificial Organs

      Volume: 33, 9 Pages: 704-713

    • Peer Reviewed
  • [Journal Article] 磁気浮上式補助人工心臓の小型化技術2009

    • Author(s)
      進士忠彦
    • Journal Title

      日本機械学会誌(日本機械学会)

      Volume: Vol.112, No.1088 Pages: 38-41

    • Peer Reviewed
  • [Journal Article] Med Tech Dispoの研究開発~Bridge-to-Bridgeを目的とした日本初,ディスポ式,磁気浮上遠心血液ポンプ,生体材料工学研究所年報2009

    • Author(s)
      長岡英気, 土方亘, 進士忠彦, 荒井裕国, 高谷節雄
    • Journal Title

      生体材料工学研究所

      Volume: Vol.43 Pages: 41-44

  • [Presentation] A Centrifugal Blood Pump Using a Single Axis Controlled Magnetic Bearing Motor2011

    • Author(s)
      Atsushi Yumoto, Tadahiko Shinshi
    • Organizer
      19th Congress of the International Society for Rotary Blood Pumps, Abstructs of 19th Congress of the International Society for Rotary Blood Pumps
    • Place of Presentation
      Kentucky, USA
    • Year and Date
      20110908-10
  • [Presentation] Less invasive extracorporeal VAD system with Med Tech Dispo : afeasibility study in animals2011

    • Author(s)
      Eiki Nagaoka, Tadahiko Shinshi, 他6名
    • Organizer
      19th Congress of the International Society for Rotary Blood Pumps, Abstructs of 19th Congress of the International Society for Rotary Blood Pumps
    • Place of Presentation
      Kentucky, USA
    • Year and Date
      20110908-10
  • [Presentation] Med Tech Dispo, A Disposable Mag-lev Centrifugal Blood Pump for ECMO or RVAD2011

    • Author(s)
      Tatsuki Fujiwara, Tadahiko Shinshi, 他6名
    • Organizer
      19th Congress of the International Society for Rotary Blood Pumps, Abstructs of 19th Congress oft he International Society for Rotary Blood Pumps
    • Place of Presentation
      Kentucky, USA
    • Year and Date
      20110908-10
  • [Presentation] Cost-effective Disposable Centrifugal Blood Pump Utilizing Maglev Technology, International2011

    • Author(s)
      Tadahiko Shinshi, Wataru Hijikata, 他1名
    • Organizer
      Symposium on Technologies against Cancer 2011
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      20110901-02
  • [Presentation] Medtech Dispo, A Disposable Mag-lev Centrifugal Blood Pump : Two-month in vivo Evaluation of Biocompatibility in LVAD Condition2010

    • Author(s)
      Eiki Nagaoka, Tadahiko Shinshi, 他6名
    • Organizer
      18th Congress of the International Society for Rotary Blood Pumps
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      20101014-16
  • [Presentation] Fault-Tolerance for a Centrifugal Blood Pump using a Two-DOFControlled Magnetic Bearing2010

    • Author(s)
      Chi Nan Pai, Tadahiko Shinshi, 他1名
    • Organizer
      ISMB12(The Twelfth International Symposium on Magnetic Bearings)
    • Place of Presentation
      Wuhan, CHINA
    • Year and Date
      20100822-25
  • [Presentation] Cost-Effective Magnetic Bearing System using a Single-Use Magnet-Less Rotor for an Extracorporeal Centrifugal Blood Pump2010

    • Author(s)
      Wataru Hijikata, Tadahiko Shinshi, 他2名
    • Organizer
      ISMB12(The Twelfth International Symposium on Magnetic Bearings)
    • Place of Presentation
      Wuhan, CHINA
    • Year and Date
      20100822-25
  • [Presentation] Sensorless Measurement of the Pulsatile Flow through an Implantable Maglev Centrifugal Blood Pump during Ventricular Assistance2009

    • Author(s)
      Chi Nan Pai, Tadahiko Shinshi, 他1名
    • Organizer
      ICROS-SICE International Joint Conference
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      20090818-21
  • [Presentation] Radial Hydraulic Force Estimation In A Magnetically Levitated Centrifugal Blood Pump2009

    • Author(s)
      Chi Nan Pai, Tadahiko Shinshi, 他2名
    • Organizer
      the 2009 JSME-IIP/ASME-ISPS Joint Conference on Micromechatronics for Information and Precision Equipment
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      20090617-20
  • [Remarks]

    • URL

      http://www.nano.pi.titech.ac.jp/

  • [Patent(Industrial Property Rights)] 使い捨て磁気浮上式遠心ポンプ2012

    • Inventor(s)
      土方亘,進士忠彦,高谷節雄
    • Industrial Property Rights Holder
      東京工業大学,東京医科歯科大学
    • Industrial Property Number
      特許、13/392, 879
    • Filing Date
      2012-02-28
    • Overseas
  • [Patent(Industrial Property Rights)] 使い捨て磁気浮上式遠心ポンプ2012

    • Inventor(s)
      土方亘,進士忠彦,高谷節雄
    • Industrial Property Rights Holder
      東京工業大学,東京医科歯科大学
    • Industrial Property Number
      特許、10811526. 2
    • Filing Date
      2012-03-20
    • Overseas
  • [Patent(Industrial Property Rights)] 使い捨て磁気浮上式遠心ポンプ2012

    • Inventor(s)
      土方亘,進士忠彦,高谷節雄
    • Industrial Property Rights Holder
      東京工業大学,東京医科歯科大学
    • Industrial Property Number
      特許、201080038326. 3
    • Filing Date
      2012-02-27
  • [Patent(Industrial Property Rights)] 使い捨て磁気浮上式遠心ポンプ2012

    • Inventor(s)
      土方亘,進士忠彦,高谷節雄
    • Industrial Property Rights Holder
      東京工業大学,東京医科歯科大学
    • Industrial Property Number
      特許、特願2011-528654
    • Filing Date
      2012-02-28
    • Overseas
  • [Patent(Industrial Property Rights)] 使い捨て磁気浮上式血液ポンプ2011

    • Inventor(s)
      進士忠彦,下河邉明,朝間淳一,原力,土方亘,高谷節雄,星英男
    • Industrial Property Rights Holder
      東京工業大学,東京医科歯科大学
    • Industrial Property Number
      特許、1932554
    • Filing Date
      2011-12-08
    • Overseas
  • [Patent(Industrial Property Rights)] 使い捨て磁気浮上式血液ポンプ2010

    • Inventor(s)
      進士忠彦,下河邉明,朝間淳一,原力,土方亘,高谷節雄,星英男
    • Industrial Property Rights Holder
      東京工業大学,東京医科歯科大学
    • Industrial Property Number
      特許、4496376
    • Filing Date
      2010-04-23
    • Overseas

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Published: 2013-07-31  

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