2012 Fiscal Year Final Research Report
Functionalization of microbes cultured in 2D on the newly developed optical feedback system
| Project/Area Number |
21360192
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
System engineering
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
OZASA Kazunari 独立行政法人理化学研究所, 前田バイオ工学研究室, 専任研究員 (10231234)
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| Research Collaborator |
SIMON Song Hanyang University, Korea, Professor
JEESOO Lee Hanyang University, Korea, Doctor course student
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| Project Period (FY) |
2009 – 2012
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| Keywords | 光フィードバック / ミドリムシ / マイクロ流路 / 光走性 / 化学走性 / ニューロコンピューティング |
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| Research Abstract |
We developed a new optical feedback system for the photoreactive microbes confined in a microfluidic device. By using the photophobic reaction of Euglena, we succeeded in the control of cell density in the micro-aquarium dynamically with arbitrary pattern. We also achieved neuro-computing by introducing neural network algorithm in the feedback algorithm, by which optimized solution can be obtained with dynamic transition. Further, we succeeded in artificial connection between two individual culture system with optical feedback as well as chemical sensing using chemotaxis of the microbes.
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