2011 Fiscal Year Final Research Report
Exploring novel human endogenous lectins and their functional analysis
| Project/Area Number |
21370062
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional biochemistry
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
HIRABAYASHI Jun 独立行政法人産業技術総合研究所, 糖鎖医工学研究センター, 副研究センター長 (40156691)
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| Co-Investigator(Kenkyū-buntansha) |
TATENO Hiroaki 独立行政法人産業技術総合研究所, 糖鎖医工学研究センター, 研究員 (30450670)
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| Project Period (FY) |
2009 – 2011
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| Keywords | レクチン / 糖鎖 / 真菌 / 免疫 |
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| Research Abstract |
In order to elucidate biological functions of glycans, it is essential to make a comprehensive approach to their partner molecules, endogeneous lectins. A considerably large number of lectin candidate molecuoles are found in the human geneome data base. Based on the information it is now possible to produce their recombinant proteins and investigate systematically their sugar-binding properties by means of advanced glycotechnologies developed in our group, e. g., glycoconjugate microarray and frontal affinity chromatography. Both of their possible roles in vivo and utilities as tools are studied.
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Research Products
(18 results)
