2012 Fiscal Year Final Research Report
A challenge to "homochirality in sugar metabolism"Analysis of L-glucose catabolic pathway
| Project/Area Number |
21380054
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
TAKAYA Naoki 筑波大学, 生命環境系, 教授 (50282322)
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| Project Period (FY) |
2009 – 2012
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| Keywords | ホモキラリティー / L-グルコース / Paracoccus / 糖代謝 |
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| Research Abstract |
Most organisms on the Earth can utilize D-glucose as carbon and energy sources, but utilization of its enantiomer, L-glucose, was not reported so far. Therefore it is generally recognized that there is a homochirality issue in sugar utilization. In this study we have analyzed, at enzyme and genetic levels, an L-glucose catabolic pathway in Paracoccus sp. 43P, an L-glucose utilizing bacterium isolated from soil, and succeeded in its elucidation for the first time. The results may contribute further understanding of homochirality issues of living organisms.
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