2011 Fiscal Year Final Research Report
Large-scale syntheses of multi-bridged peptides that require complicated synthetic processes
| Project/Area Number |
21380072
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
CHIBA Kazuhiro 東京農工大学, 大学院・農学研究院, 教授 (20227325)
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| Project Period (FY) |
2009 – 2011
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| Keywords | ペプチド / 化学合成 / 立体構造 / 生体分子 / 生物活性 |
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| Research Abstract |
Large-scale synthetic method for multi-bridged peptides was investigated to overcome their synthetic difficulties. By introducing reverse-micelle reaction field, condensation reactions and selective intramolecular bridge-formations took place efficiently to achieve the chemical synthetic method of the peptides with high-purity, high-yield, and ease of handling.
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Research Products
(66 results)
