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2011 Fiscal Year Final Research Report

Basic and Applied Research on Integrated Nutriomics Encompassing Various Aspects of Lifestyle

Research Project

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Project/Area Number 21380076
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Food science
Research InstitutionThe University of Tokyo

Principal Investigator

KATO Hisanori  東京大学, 総括プロジェクト機構, 特任教授 (40211164)

Project Period (FY) 2009 – 2011
Keywordsニュートリゲノミクス / 遺伝子発現 / 栄養 / 生活習慣 / 運動 / 日内リズム
Research Abstract

Methods for analyzing huge kinds of biological molecules, which are so called "omics" methods, were employed to exhaustively examine the response of animals to consumption of specific foods. Multiple exhaustive analyses including those for the levels of mRNA, proteins, and metabolites were combined. Efforts were made to improve a database and an analytical tool for the promotion of these types of researches, and their effectiveness was proved. The effects of factors relating to dietary habits, which include exercise and circadian rhythm were also examined.

  • Research Products

    (23 results)

All 2012 2011 2010 2009 Other

All Journal Article (7 results) (of which Peer Reviewed: 6 results) Presentation (10 results) Book (4 results) Remarks (2 results)

  • [Journal Article] Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats2012

    • Author(s)
      Otani, L., Sugimoto, N., Kaji, M., Murai, M., Chang, S.-J., Kato, H. and Murakami, T
    • Journal Title

      J. Nutr. Biochem

      Volume: (印刷中)

    • DOI

      DOI:10.1016/j.jnutbio.2011.04.014

    • Peer Reviewed
  • [Journal Article] Omics and integrated omics for the promotion of food and nutrition science2011

    • Author(s)
      Kato, H., Takahashi, S. and Saito, K
    • Journal Title

      J. Trad. Comp. Med

      Volume: 1 Pages: 25-30

    • DOI

      DOI:10.6219/jtcm.2011.009-R

  • [Journal Article] Mild caloric restriction up-regulates the expression of prohibitin2011

    • Author(s)
      Takahashi, S., Masuda, J., Shimagami, H., Ohta, Y., Kanda, T., Saito, K. and Kato, H
    • Journal Title

      A proteome study. Biochem. Biophys. Res. Commun

      Volume: 405 Pages: 462-467

    • DOI

      DOI:10.1016/j.bbrc.2011.01.054

    • Peer Reviewed
  • [Journal Article] Feeding-induced rapid resetting of the hepatic circadian clock is associated with acute induction of Per2 and Dec1 transcription in rats2010

    • Author(s)
      Wu, T., Ni, Y., Kato, H. and Fu, Z
    • Journal Title

      Chronobiol. Int

      Volume: 27 Pages: 1-18

    • DOI

      DOI:10.3109/07420520903398625

    • Peer Reviewed
  • [Journal Article] Dietary iron deficiency induces a variety of metabolic changes and even apoptosis in rat liver : a DNA microarray study.2010

    • Author(s)
      Kamei, A., Watanabe, Y., Ishijima, T., Uehara, M., Arai, S., Kato, H., Nakai, Y. and Abe, K
    • Journal Title

      Physiol. Genomics

      Volume: 42 Pages: 149-156

    • DOI

      DOI:10.1152/physiolgenomics.00150.2009

    • Peer Reviewed
  • [Journal Article] Regulation of circadian gene expression in the kidney by light and food cues in rats2010

    • Author(s)
      Wu, T., Ni, Y., Dong, Y., Kato, H. and Fu, Z. W
    • Journal Title

      Am. J. Physiol. Regul. Integr. Comp. Physiol

      Volume: 298 Pages: 635-641

    • DOI

      DOI:10.1152/ajpregu.00578.2009

    • Peer Reviewed
  • [Journal Article] Effect of mild restriction of food intake on gene expression profile in the liver of young rats : reference data for in vivo nutrigenomics study.2010

    • Author(s)
      Saito, K., Ohta, Y., Sami, M., Kanda, T. and Kato, H
    • Journal Title

      Brit. J. Nutr

      Volume: 104 Pages: 941-950

    • DOI

      DOI:10.1017/S0007114510001625

    • Peer Reviewed
  • [Presentation] 統合オミクス技術と食品機能性解析第6回核酸2011

    • Author(s)
      加藤久典
    • Organizer
      核タンパク機能性研究会学術大会
    • Place of Presentation
      北海道恵庭市
    • Year and Date
      2011-08-08
  • [Presentation] Mild caloric restriction up-regulates the expression of prohibitin : A proteome study2011

    • Author(s)
      Takahashi, S., Masuda, J., Shimagami, H., Ohta, Y., Kanda, T., Saito, K., Kato, H
    • Organizer
      11th Asian Congress of Nutrition
    • Place of Presentation
      シンガポール
    • Year and Date
      2011-07-15
  • [Presentation] Keggle : Web-based visualization tool of omics data for the promotion of nutri-omics study2011

    • Author(s)
      Saito, K. and Kato, H
    • Organizer
      11th Asian Congress of Nutrition
    • Place of Presentation
      シンガポール
    • Year and Date
      2011-07-15
  • [Presentation] 網羅的解析技術による食品の機能性研究の現状2011

    • Author(s)
      加藤久典
    • Organizer
      第65回日本栄養・食糧学会大会
    • Place of Presentation
      お茶の水女子大学
    • Year and Date
      2011-05-15
  • [Presentation] 穏やかなカロリー制限によるProhibitinの発現上昇2011

    • Author(s)
      高橋祥子、桝田旬子、島上洋、太田豊、神田智正、斉藤憲司、加藤久典
    • Organizer
      2011年日本農芸化学会大会
    • Place of Presentation
      京都女子大学(京都府)
    • Year and Date
      2011-03-26
  • [Presentation] ニュートリオミクスがもたらす栄養学の新展開2010

    • Author(s)
      加藤久典
    • Organizer
      日本農芸化学会関東支部大会
    • Place of Presentation
      近畿大学(奈良県)
    • Year and Date
      2010-10-02
  • [Presentation] 食品因子・運動負荷・薬剤がラット肝脂質代謝に与える影響のトランスクリプトーム解析2010

    • Author(s)
      斉藤憲司、小笠原由貴、加藤久典
    • Organizer
      第64回日本栄養・食糧学会大会
    • Place of Presentation
      アスティ徳島(徳島県)
    • Year and Date
      2010-05-23
  • [Presentation] SHRSPラットにおける胎児期の低タンパク質栄養に起因する食塩感受性亢進機構のトランスクリプトーム解析2010

    • Author(s)
      大谷りら、斉藤憲司、末安俊明、村上哲男、加藤久典
    • Organizer
      第64回日本栄養・食糧学会大会
    • Place of Presentation
      アスティ徳島(徳島県)
    • Year and Date
      2010-05-23
  • [Presentation] Transgenerational Effects of Maternal Protein Restriction During Pregnancy on Salt Sensitivity and Life Span in Stroke-Prone Spontaneously Hypertensive Rats(SHRSP)2009

    • Author(s)
      Otani, L., Murakami, T. and Kato, H
    • Organizer
      19th International Congress of Nutrition
    • Place of Presentation
      BITEK(バンコク)
    • Year and Date
      2009-10-09
  • [Presentation] Data Storage and Comparative Analysis of Gene Expression Profiles for Promotion of Nutrigenomics Study2009

    • Author(s)
      Saito, K., Ohta, Y., Sami, M., Kanda, T. and Kato, H
    • Organizer
      19th International Congress of Nutrition
    • Place of Presentation
      BITEK(バンコク)
    • Year and Date
      2009-10-06
  • [Book] 基礎栄養学2012

    • Author(s)
      佐藤隆一郎、加藤久典
    • Total Pages
      160
    • Publisher
      学文社
  • [Book] バイオチップ実用化ハンドブック2010

    • Author(s)
      加藤久典、斉藤憲司
    • Total Pages
      346-352
    • Publisher
      エヌ・ティー・エス
  • [Book] Genomics, proteomics, and metabolomics in nutraceuticals and functional foods2010

    • Author(s)
      Abe, K., Kato, H., Yasuoka, A. and Nakai, Y.
    • Total Pages
      127-154
    • Publisher
      Wiley-Blackwell
  • [Book] 食の安全科学の展開-食のリスク予測と制御に向けて2010

    • Author(s)
      加藤久典
    • Total Pages
      98-102
    • Publisher
      シーエムシー出版
  • [Remarks]

    • URL

      http://www.nutrigenomics.jp

  • [Remarks]

    • URL

      http://www.keggle.jp

URL: 

Published: 2013-07-31  

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