2011 Fiscal Year Final Research Report
Analysis on the control of oxidative stress derived from overproduction by inflammation reaction and suppression by Antioxidative Food Factors
| Project/Area Number |
21380080
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Aichi Gakuin University (2010-2011)
Nagoya University (2009) |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
UENO Yuki 愛知学院大学, 心身科学部, 講師 (20388060)
MOCHIDUKI Mika 愛知学院大学, 心身科学部, 助手 (60513091)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 酸化ストレス / 脳内老化 / 好中球 / 脂質ヒドロペルオキシド・アラキドン酸 / ドコサヘキサエン酸 / 未病診断 / モノクローナル抗体 |
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| Research Abstract |
Immunocyte is important for biophylaxis, however, overproductionof oxidative stress can be produced during the inflammation reaction, and interacts withmany biological components such as proteins, phospholipids and DNA. We have alsosucceeded in construction of novel biomarkers specific to overproduction of oxidativestress during inflammation process by chemical and immunological approach and developmentof “antibody chip” by application of these biomarkers. We also succeeded in functionalevaluation of antioxidative food factors such as soy isoflavonoids, curcuminoid andsesame rignans.
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[Presentation]2011
Author(s)
日坂真輔、林佳美、大澤俊彦
Organizer
第84回日本生化学会大会
Place of Presentation
国立京都国際会館(京都府)
Year and Date
20110921-24
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