2011 Fiscal Year Final Research Report
Development of oxoammonium-salt-type catalysts for highly enantioselective oxidation of alcohols
| Project/Area Number |
21390001
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SHIBUYA Masatoshi 東北大学, 大学院・薬学研究科, 助教 (40359534)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 有機触媒 / 酸化反応 / オキソアンモニウム塩 / ニトロキシド / 不斉反応 |
|---|
| Research Abstract |
We have developed organocatalytic highly enatiolselecitve oxidation of alcohols based on chiral modifications of 2-azaadamantane N-oxy (AZADO)-derived oxoammonium salts. The chiral AZADOs enabled a highly enantioselecitive kinetic oxidation of racemic secondary alcohols with a broad substrate applicability.
|
Research Products
(13 results)
