2011 Fiscal Year Final Research Report
Development of New Catalytic Control Methods of Chemoselectivity Using Multinuclear Metal Clusters
| Project/Area Number |
21390003
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Kyushu University (2010-2011)
Osaka University (2009) |
|---|
Principal Investigator |
OHSHIMA Takashi 九州大学, 大学院・薬学研究院, 教授 (10313123)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 金属クラスター / 触媒 / 環境調和 / 化学選択性 |
|---|
| Research Abstract |
We succeeded in the development of(1) practical synthetic method of Trifluoroacetic Acid Adduct of Trifluoroacetate-Bridged Tetranuclear Zinc Cluster,(2) the Zn cluster-catalyzed acetylation and deacetylation reactions,(3) acceleration of the Zn cluster-catalyzed transesterification by the addition of alkylamines or N-heterocyclic compounds,(4) Pt-catalyzed direct amination of allylic alcohols under mild conditions,(5) Au-catalyzed direct substitution of the hydroxy group with highly functionalized nitrogen nucleophiles,(6) C1-Symmetric Rh-Phebox-Catalyzed Asymmetric Alkynylation ofα-Keto Ester, and so on.
|
