2011 Fiscal Year Final Research Report
Fluorinated Medicines : Drug Development based on Functional Groups
| Project/Area Number |
21390030
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Drug development chemistry
|
|---|
| Research Institution | Nagoya Institute of Technology |
|---|
Principal Investigator |
SHIBATA Norio 名古屋工業大学, 大学院・工学研究科, 教授 (40293302)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 医薬品化 / 有機化学 / フッ素 / 創薬 / 不斉合成 / 生理活性物質 |
|---|
| Research Abstract |
We have developed the novel trifluoromethylation and monofluoromethylation reaction toward for drug development and the methods were applied to the synthesis of biologically attractive molecules.
|
Research Products
(47 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] 2-Fluoro-1, 3-benzodithiole-1, 1, 3, 3-tetraoxide : A Reagent for Nucleophilic Monofluoromethylation of Aldehydes2010
Author(s)
Tatsuya Furukawa, Yosuke Goto, Jumper Kawazoe, Etsuko Tokunaga, Shuichi Nakamura, Yudong Yang, Hongguang Du, Akikazu Kakehi, Mo too Shire, Norio Shibata
-
Journal Title
Angew. Chem. Mt. Ed
Volume: 49(9)
Pages: 1642-1647
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
