2011 Fiscal Year Final Research Report
Molecular analysis of physiological phenomena of Legionella expressed in the environment
| Project/Area Number |
21390131
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
FUJII Jun (60271441)
IIDA Ken-ichiro (00346777)
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| Project Period (FY) |
2009 – 2011
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| Keywords | レジオネラ / 細胞内寄生 / 糖代謝 / 環境 / 生理学 |
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| Research Abstract |
Legionellae cause pneumonia in humans. Microbes that cause pneumonia usually live in the upper-respiratory organs and infect humans by droplets. In contrast, Legionella organisms are living in the environment such as surface water and soil. Hence, to totally understand Legionella infection, it is important to know how Legionella survives under environmental stress. One of their remarkable characteristics is their ability to grow in amoeba. They also have other abilities to survive in environmental stresses like low temperatures, low nutrition, etc. In this study, we tried to elucidate(1) the molecular mechanism by which they are able to grow in the amoeba at low temperature,(2) glucose metabolism which enables intracellular growth, and(3) micromillieu for intracellular bacterial growth in the host cells.
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Research Products
(9 results)
