2011 Fiscal Year Final Research Report

A cohort study on relationship of tea/coffee drinking, dietary and exercise habits with cardiovascular events and diabetes mellitus, and seroepidemiological analyses on the roles of some biomarkers in predicting the risk of these diseases

Research Project

Project/Area Number	21390204
Research Category	Grant-in-Aid for Scientific Research (B)
Allocation Type	Single-year Grants
Section	一般
Research Field	Public health/Health science
Research Institution	新潟県立大学 (2011) Niigata University (2009-2010)
Principal Investigator	TANABE Naohito 新潟県立大学, 人間生活学部, 教授 (40270938)
Project Period (FY)	2009 – 2011
Keywords	疫学
Research Abstract	Within 8, 648 participants of our cohort which was built up in 1998, 300 first ever cardiovascular(CVD) events were observed by the end of 2008. Ninety-eight participants were diagnosed to be type 2 diabetes mellitus(T2DM) within the period between the 12th month from baseline and the end of 2008. Habitual consumptions of green tea and milk were associated with decreased risk of total CVD events whereas imbalanced intake of meat and fish, infrequent intake of light-colored vegetables and fruits, and high consumption of rice and grain products were associated with the elevated risk. Low intake of fish and meat was associated with development of T2DM. As for biomarkers measured from stored serum, high-sensitivity CRP was positively associated with the risk of total CVD, ischemic heart disease(IHD) and T2DM ; uric acid was positively associated with the risk of T2DM ; LDL cholesterol was positively associated with and T2DM ; and total bilirubin was negatively associated with the risk of T2DM.

(2 results)