2011 Fiscal Year Final Research Report
An epidemiological study on the association between habitual alcohol drinking and risk factors for atherosclerotic disease in the elderly
| Project/Area Number |
21390211
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MARUMO Mikio 兵庫医科大学, 医学部, 講師 (40333950)
NAKANO Tomoyuki 兵庫医科大学, 医学部, 助教 (00333948)
TAKAHASHI Yuji 兵庫医科大学, 医学部, 非常勤講師 (20292443)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 社会医学 / 加齢医学 / 飲酒習慣 / 動脈硬化 |
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| Research Abstract |
Both beneficial and harmful aspects exist in the effects of habitual alcohol drinking on atherosclerotic risk factors. HDL cholesterol is higher in drinkers than in nondrinkers, while LDL cholesterol is lower in drinkers than in nondrinkers. Risk of obesity or hyperglycemia is lower in drinkers than in nondrinkers. These beneficial effects of drinking were less prominent in the older group than in the younger group. On the other hand, harmful effect of drinking is mainly explained by alcohol-induced hypertension. Increase in blood pressure in drinkers compared with nondrinkers was more prominent in the older group than in the younger group. Therefore, the limit of alcohol intake should be lower in older people than in younger people from the viewpoint of prevention of atherosclerotic disease.
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[Journal Article] Which of high-sensitivity C-reactive protein and low-density lipoprotein cholesterol shows a stronger relationship with the cardio-ankle vascular index in healthy community dwellers : the KOBE study2012
Author(s)
Higashiyama A, Wakabayashi I, Kubota Y, Adachi Y, Hayashibe A, Nishimura K, Sugiyama D, Kadota A, Imano H, Miyamatsu N, Miyamoto Y, Okamura T.
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Journal Title
J Atheroscler Thromb
Volume: (印刷中)
Peer Reviewed
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