2011 Fiscal Year Final Research Report
Genome-wide association study identifies two susceptibility loci for agerelated macular degeneration in the Japanese population
| Project/Area Number |
21390468
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KIYOHARA Yutaka 九州大学, 大学院・医学研究院, 教授 (80161602)
KUBO Mitsuaki 独立法人理化学研究所, チームリーダー (30442958)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 加齢黄斑変性 / 遺伝子解析 / ゲノムワイドアプローチ |
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| Research Abstract |
Our data showed that TNFRSFIOALOC389641 on chromosome 8p21 and RESTC4orf14POLR2BIGFBP7 on chromosome 4q12 are new susceptibility loci for exudative AMD in the Japanese population. Futher functional studies are neccesary to clarify the mechanisms of these loci on the susceptibility to exudative AMD
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