2012 Fiscal Year Final Research Report
Mechanisms of salivary gland atrophy induced by soft food
| Project/Area Number |
21390499
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WAKITA Minoru 北海道大学, 副学長 (40018916)
YAMAMOTO Tsuneyuki 北海道大学, 大学院・歯学研究科, 准教授 (80200822)
FUNAHASHI Makoto 北海道大学, 大学院・歯学研究科, 教授 (80221555)
IIZUKA Tadashi 北海道大学, 大学院・歯学研究科, 准教授 (80168062)
YOSHIMURA Yoshitaka 北海道大学, 大学院・歯学研究科, 助教 (30230816)
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| Project Period (FY) |
2009 – 2012
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| Keywords | ソフトフード / 唾液腺 / 萎縮 |
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| Research Abstract |
Salivary glands of rats fed a liquid diet for 3 weeks were investigated microscopically to clarify the effects of soft food on salivary glands. Parotid glands of experimental rats became atrophic after liquid diet feeding, and cell shrinkage, cell death, and reduction of speed of cell-cycle were identified in the atrophic parotid glands. However, such atrophic alterations were not observed in submandibular and sublingual glands following liquid diet feeding. These observations suggest that it depends on the kind of salivary glands whether liquid diet feeding induces atrophy to the salivary glands.
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Research Products
(23 results)
