2011 Fiscal Year Final Research Report
Trial of regeneration therapy for salivary gland using gene expression database
| Project/Area Number |
21390534
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
SAKAI Takayoshi 大阪大学, 大学院・歯学研究科, 教授 (90379082)
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| Co-Investigator(Kenkyū-buntansha) |
NOHARA Kanji 大阪大学, 歯学部附属病院, 助教 (20346167)
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| Co-Investigator(Renkei-kenkyūsha) |
FUKUMOTO Satoshi 東北大学, 大学院・歯学研究科, 教授 (30264253)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 臓器 / 再生 / 唾液腺 / 分枝 / 形態形成 / 口腔乾燥症 |
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| Research Abstract |
The aim of this research is to clarify the molecular mechanism of organ formation for the new treatment of dry mouth. Global database of gene expression in salivary gland epithelia from cleft and bud were profiled, and new genes that could be important for branching morphogenesis were explored.
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