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2012 Fiscal Year Annual Research Report

認知症の早期診断と社会対策の最先端研究および国際最新状況に関する海外調査研究

Research Project

Project/Area Number 21404002
Section海外学術
Research InstitutionOkayama University

Principal Investigator

呉 景龍  岡山大学, 自然科学研究科, 教授 (30294648)

Co-Investigator(Kenkyū-buntansha) 高橋 智  岡山大学, 自然科学研究科, 准教授 (20236277)
楊 家家  岡山大学, 自然科学研究科, 助教 (30601588)
峠 哲男  香川大学, 医学部, 教授 (80197839)
福山 秀直  京都大学, 医学(系)研究科(研究院), 教授 (90181297)
Project Period (FY) 2009-04-01 – 2013-03-31
Keywords認知症 / 早期診断 / 脳波 / 画像診断 / fMRI / 視覚 / 聴覚 / 触覚
Research Abstract

平成24年度も代表者と分担者が,医学出身と工学出身の海外研究者と院生を含む国内研究者の協力を得て,欧米やアジアへの現地訪問や通信調査などの手段を用いて,(1)海外での認知症調査研究,(2)認知症診断技術の国際基準の提案,および(3)認知症社会対策の提言を目指して調査研究を実施した.
共同研究者を通じて海外の認知症に関する研究者と連絡を取り,認知症の早期診断と客観的な判断基準の制定が重要であるという共通認識のもとに,認知症に関する認知実験,画像診断,生体信号測定などの実験結果を集め,検討を行った.特に触覚による認知機能の客観的評価方法の有効性を確かめるため,病院などでの臨床実験が可能で汎用性の高い検査装置の設計・制作に取り掛かった.また中国だけでなく,共同研究者を通じてヨーロッパの研究者とも連絡を取り,大規模な臨床実験に向けた計画の立案等装置の開発及び患者データの共有に向けた取り組みを行った.また日本国内の研究分担者間でも画像診断に関する測定結果を持ち寄り,認知機能に関する検討を行った.
これまで4年間の,認知症診断国際基準の提案に向けた基礎データの収集,解析,評価,および認知症診断に関する早期診断技術,波形診断技術,画像診断技術へのフィードバックを元に,本研究終了後も引き続き研究代表者,研究分担者間で情報を共有し,研究を進める.

Current Status of Research Progress
Reason

24年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

24年度が最終年度であるため、記入しない。

  • Research Products

    (46 results)

All 2013 2012

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (36 results) (of which Invited: 2 results) Book (2 results)

  • [Journal Article] Enhancement of Visual Detection by Temporal Alignment of Visual-auditory Stimuli: A Behavioral and Event-Related Potential Study2013

    • Author(s)
      Jingjing Yang
    • Journal Title

      Information

      Volume: Vol.16, No.1(A) Pages: 527-534

    • Peer Reviewed
  • [Journal Article] 視覚誘導自己直線運動感覚の空間特性の輝度依存性2013

    • Author(s)
      呉景龍
    • Journal Title

      人間工学

      Volume: Vol.49, No.1 Pages: 18-24

    • Peer Reviewed
  • [Journal Article] Prominent Activation of the Intraparietal and Somatosensory Areas during Angle Discrimination by Intra-Active Touch2012

    • Author(s)
      Jiajia Yang, Hongbin Han, Dehua Chui, Yong Shen, Jinglong Wu
    • Journal Title

      Human Brain Mapping

      Volume: Vol.33, No.12 Pages: 2957-2970

    • Peer Reviewed
  • [Journal Article] The Ebbinghaus Illusion Affects Visual Size Perception But Not Pointing Movement2012

    • Author(s)
      Jiajia Yang, Disuke Oka, Jinglong Wu
    • Journal Title

      Information

      Volume: Vol.15(4) Pages: 1799-1808

    • Peer Reviewed
  • [Journal Article] Prominent activation of the bilateral inferior parietal lobule of literate compared with illiterate subjects during Chinese logographic processing2012

    • Author(s)
      Jinglong Wu
    • Journal Title

      Experimental Brain Research

      Volume: Vol.219 Pages: 372-337

    • Peer Reviewed
  • [Journal Article] Age-related multisensory integration elicited by peripherally presented audiovisual stimuli2012

    • Author(s)
      Jinglong Wu
    • Journal Title

      NeuroReport

      Volume: Vol.23 Pages: 616-620

    • Peer Reviewed
  • [Journal Article] Retinotopic Mapping of the Peripheral Visual Field to Human Visual Cortex by Functional Magnetic Resonance Imaging2012

    • Author(s)
      Jinglong Wu
    • Journal Title

      Human Brain Mapping

      Volume: Vol.33, Issue 7 Pages: 1727-1740

    • Peer Reviewed
  • [Journal Article] Delayed Audiovisual Integration of Patients with Mild Cognitive Impairment and Alzheimer's Disease Compared with Normal Aged Controls2012

    • Author(s)
      Jinglong Wu
    • Journal Title

      Journal of Alzheimer Disease

      Volume: Vol.32 Pages: 317-328

    • Peer Reviewed
  • [Presentation] 視覚空間注意における左右の注意の切り替えに関するfMRI検討2012

    • Author(s)
      宮本豪士
    • Organizer
      第45回日本人間工学会中国・四国支部大会
    • Place of Presentation
      岡山
    • Year and Date
      20121215-20121215
  • [Presentation] 視聴覚分割注意タスクにおける多感覚統合の加齢効果に関する研究2012

    • Author(s)
      楊偉平
    • Organizer
      第45回日本人間工学会中国・四国支部大会
    • Place of Presentation
      岡山
    • Year and Date
      20121215-20121215
  • [Presentation] 中国語処理における文盲と非文盲者の後方下前頭回の違いに関するfMRI研究2012

    • Author(s)
      王彬
    • Organizer
      第45回日本人間工学会中国・四国支部大会
    • Place of Presentation
      岡山
    • Year and Date
      20121215-20121215
  • [Presentation] 触覚空間ワーキングメモリ研究のための装置の開発と評価2012

    • Author(s)
      呉景龍
    • Organizer
      第45回日本人間工学会中国・四国支部大会
    • Place of Presentation
      岡山
    • Year and Date
      20121215-20121215
  • [Presentation] Early Detection of Dementia by Tactile and Visual-auditory Approach2012

    • Author(s)
      Jinglong Wu
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121021-20121021
    • Invited
  • [Presentation] Study on the Human Visual Mechanism of Wide-field by fMRI2012

    • Author(s)
      Satoshi Takahashi
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121021-20121021
    • Invited
  • [Presentation] 広視野における顔と家の認識領域の非線形決定手法2012

    • Author(s)
      王 彬
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 中国語処理における文盲と非文盲者の後頭側頭皮質活動差異に関するfMRI研究2012

    • Author(s)
      其格其
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 持続的と非持続的なキューを用いたポズナータスクに関する脳活動の比較2012

    • Author(s)
      李玉傑
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 単純な視聴覚判断タスクにおいて加齢効果が多感覚統合に及ぼす影響2012

    • Author(s)
      楊偉平
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 触覚角度弁別を用いた認知症スクリーニング装置の開発及び評価2012

    • Author(s)
      モハマド・ウサイリー
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 非持続キューにおける視覚空間能動注意課題を用いた加齢効果に関するfMRI研究2012

    • Author(s)
      河田祐也
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 若年者と高齢者における把持動作の長さ弁別能力の検討2012

    • Author(s)
      郷宗充
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] Resting-state networks (RSNs)における加齢効果についてのfMRI研究2012

    • Author(s)
      加茂直人
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 触覚格子弁別課題を用いたワーキングメモリの加齢効果に関する研究2012

    • Author(s)
      後藤綾介
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 若年者と高齢者における長さ弁別課題を用いたワーキングメモリの調査2012

    • Author(s)
      武之偉
    • Organizer
      医工学国際シンポジウム in 大山
    • Place of Presentation
      鳥取
    • Year and Date
      20121020-20121020
  • [Presentation] 視聴覚統合における健常高齢者と認知症患者の差異2012

    • Author(s)
      高玉林
    • Organizer
      第3回日本血管性認知症研究会
    • Place of Presentation
      東京
    • Year and Date
      20120908-20120908
  • [Presentation] 臨床用の触覚角度弁別装置の開発および認知症早期発見への応用2012

    • Author(s)
      Mohd Usairy Syafiq
    • Organizer
      第3回日本血管性認知症研究会
    • Place of Presentation
      東京
    • Year and Date
      20120908-20120908
  • [Presentation] Inhibition of Tactile Information on Visual Spatial Attention: An fMRI Study2012

    • Author(s)
      Qiong Wu
    • Organizer
      2012 IEEE International Conference on Mechatronics and Automation (ICMA2012)
    • Place of Presentation
      中国・成都
    • Year and Date
      20120808-20120808
  • [Presentation] Effect of Spatial Smoothing on Regions of Interested Analysis basing on General Linear Model2012

    • Author(s)
      Bin Wang
    • Organizer
      2012 IEEE International Conference on Mechatronics and Automation (ICMA2012)
    • Place of Presentation
      中国・成都
    • Year and Date
      20120807-20120807
  • [Presentation] Effect of cue-target interval on temporally endogenous attention of No-Go target: Event-related potential evidence2012

    • Author(s)
      Yulin Gao
    • Organizer
      2012 IEEE International Conference on Mechatronics and Automation (ICMA2012)
    • Place of Presentation
      中国・成都
    • Year and Date
      20120807-20120807
  • [Presentation] Multisensory integration of peripherally presented audiovisual stimuli in older adults: An event-related potential study2012

    • Author(s)
      Weiping Yang
    • Organizer
      2012 IEEE International Conference on Mechatronics and Automation (ICMA2012)
    • Place of Presentation
      中国・成都
    • Year and Date
      20120806-20120806
  • [Presentation] A new vision for BioMedicine: a Systems Approach2012

    • Author(s)
      Jaime Gomez-Ramirez
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120704-20120704
  • [Presentation] Effect of cue-target interval on endogenous attention in Go/No-Go task: evidence from an event-related potentials study2012

    • Author(s)
      Xiaoyu Tang
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120704-20120704
  • [Presentation] Neural Correlates of Tactile Orientation Discrimination: an fMRI Study2012

    • Author(s)
      Yinghua Yu
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120704-20120704
  • [Presentation] Using Multi-voxel Pattern Analysis of fMRI Data to Decoding Human Visual Cortex Activations2012

    • Author(s)
      Liye Wang
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120704-20120704
  • [Presentation] Effects of Spatial Location on Bisensory Audivisual Integration in Horizontal Meridian2012

    • Author(s)
      Qi Li
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] Development and Evaluation of a tactile speed stimulator for MRI environment2012

    • Author(s)
      Min Guo
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] Differential activity of semantic and font size judgment processing of Japanese word: an fMRI study2012

    • Author(s)
      Xiujun Li
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] Behavioral Evidence of Delay-Dependent Tactile Length Discrimination2012

    • Author(s)
      Zhiwei Wu
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] The Effect of Spatial Information of Auditory Stimuli on Audiovisual Interaction: Evidence from Event-related Potentials2012

    • Author(s)
      Jingjing Yang
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] Middle temporal gyrus and sub-cortical areas are related to exdogenous temporal expectation2012

    • Author(s)
      Chunlin Li
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] Visual Temporal Cuing Effect on the Tactile Attention: An fMRI Study2012

    • Author(s)
      Qiong Wu
    • Organizer
      2012 ICME International Conference on Complex and Medical Engineering (CME2012)
    • Place of Presentation
      神戸
    • Year and Date
      20120702-20120702
  • [Presentation] Comparison of auditory top-down spatial and temporal attention: an fMRI study2012

    • Author(s)
      Chunlin Li
    • Organizer
      18th Annual Meeting of the Organization for Human Brain Mapping, (OHBM2012)
    • Place of Presentation
      中国・北京
    • Year and Date
      20120614-20120614
  • [Presentation] A MRI-Compatible Tactile Orientation Stimulator to Investigate Brain Activation of Tactile Memory2012

    • Author(s)
      Yinghua Yu
    • Organizer
      18th Annual Meeting of the Organization for Human Brain Mapping, (OHBM2012)
    • Place of Presentation
      中国・北京
    • Year and Date
      20120612-20120612
  • [Presentation] Aging effect on pedal errors of driving under different visual conditions2012

    • Author(s)
      Masayuki Yoshitake, Jiajia Yang, Jinglong Wu
    • Organizer
      International Conference on Advanced Mechatronic systems (ICAMechS2012)
    • Place of Presentation
      東京
    • Year and Date
      2012-09-19
  • [Book] Technical Advancements in Biomedicine for Healthcare Applications2012

    • Author(s)
      Jinglong Wu
    • Total Pages
      477
    • Publisher
      IGI Global
  • [Book] Biomedical Engineering and Cognitive Neuroscience for Healthcare: Interdisciplinary Applications2012

    • Author(s)
      Jinglong Wu
    • Total Pages
      456
    • Publisher
      IGI Global

URL: 

Published: 2014-07-24  

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