2011 Fiscal Year Final Research Report
Development of surveillance tools for eradication of schistosomiasis japonica applicable for the endemic areas in China
| Project/Area Number |
21406008
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
OHTA Nobuo 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (10143611)
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| Co-Investigator(Renkei-kenkyūsha) |
NIHEI Naoko 国立感染症研究所, 国立感染症研究所・昆虫医科昆虫医科学部, 客員研究員 (70425677)
KUMAGAI Takashi 東京医科歯科大学, 大学院・医歯学総合研究科, 助教 (40369054)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 蠕虫 / 日本住血吸虫 / DNA診断 / LAMP / Oncomelania |
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| Research Abstract |
New surveillance tools for schistosomiasis control were developed and tested in endemic foci in China. LAMP method was confirmed to be an easy method of high sensitivity and specificity, which could be applied for on-site use without special equipments. Together with those simple and reliable tools, epidemiological surveillance using GIS for evaluating risk factors of bleeding snail hosts should be introduced especially for big endemic fields like those in China. By the use of those new tools, more effective strategy for eliminating schistosomiasis japonica was proposed for endemic foci in China.
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[Journal Article] Schistosomicidal and anti-fecundity effects of oral treatment of synthetic endperoxide compound N-892011
Author(s)
Taniguchi T, Kumagai T, Shimogawara R, Ichinose S, Hiramoto A, Sato A, Morita M, Nojima M, Kim HS, Wataya Y, Ohta N
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Journal Title
Parasitol Int
Volume: 60
Pages: 231-6
Peer Reviewed
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[Journal Article] Cerebral schistosomiasis due to Schistosoma haematobium confirmed by PCR analysis of brain specimen2011
Author(s)
Imai K, Koibuchi T, Kumagai T, Maeda T, Osada Y, Ohta N, Koga M, Nakamura H, Miura T, Iwamoto A, Fujii T
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Journal Title
J Clin Microbiol
Volume: 49
Pages: 3703-6
Peer Reviewed
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[Journal Article] Schistosome eggs have a direct role in the induction of basophils capable of a high level of IL-4 production : Comparative study of single-and bisexual infection of Schistosoma mansoni in vivo2010
Author(s)
Anyan WK, Kumagai T, Shimogawara R, Seki T, Akao N, Obata K, Bentum BK, Bosompem BK, BoakyeDA, Wilson MD, Karasuyama H, Ohta N
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Journal Title
Trop Med Health
Volume: 38
Pages: 1-12
Peer Reviewed
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