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2011 Fiscal Year Final Research Report

Finding Medical Knowledge from Clinical Data based on Interpretations

Research Project

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Project/Area Number 21500135
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Intelligent informatics
Research InstitutionJapan Advanced Institute of Science and Technology

Principal Investigator

KAWASAKI Saori  北陸先端科学技術大学院大学, 先端領域社会人教育院, 特任准教授 (40377437)

Co-Investigator(Kenkyū-buntansha) TU Bao Ho  北陸先端科学技術大学院大学, 知識科学研究科, 教授 (60301199)
Co-Investigator(Renkei-kenkyūsha) TAKABAYASHI Katsuhiko  千葉大学, 医学部附属病院, 教授 (90188079)
KANDA Tatsuo  千葉大学, 医学研究院, 特任講師 (20345002)
Project Period (FY) 2009 – 2011
Keywordsデータマイニング / 医療データ / 専門知識 / 後処理 / 解釈モデル
Research Abstract

The focus of this research is to obtain more interesting mining results for the medical experts, so that not only the data mining from the target clinical data itself but also the combining the background knowledge extraction from medical litarature and experts’interpretations have been pursued in finding the relationships among blood tests and the treatment effects. dditionally, in accordance with the high attention to sequence analysis in biomedicine, semi-supervised learning methods specially for the virus subgenotypes and the interferon/ribavirin treatments were developed to show the potentials of computational approaches.

  • Research Products

    (19 results)

All 2013 2012 2011 2010 2009

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (10 results) Book (2 results)

  • [Journal Article] Quantitatively assessing the effect of regulatory factors on nucleosome dynamics, Journal of Ambient Intelligence and Humanized Computing2013

    • Author(s)
      Ho, B.H., Le, N.T., Ho, T.B.
    • Journal Title

      Peer Reviewed

      Volume: Vol. 3, Issue 4 Pages: 265-280

    • Peer Reviewed
  • [Journal Article] Detecting Disease Genes Based on Semi-Supervised Learning and Protein-Protein Interaction Networks, Artificial Intelligence in Medicine2013

    • Author(s)
      Nguyen, T.P., Ho, T.B.
    • Journal Title

      Peer Reviewed

      Volume: Vol. 54 Pages: 63-71

    • Peer Reviewed
  • [Journal Article] A Semi-Supervised Learning Method for Discriminative Motif Finding and Its Application, Journal of Universal Computer Science2012

    • Author(s)
      Le, N., Ho, T.B., Kanda, T., Kawasaki,S., Takabayashi, K., Wu, S., Yokosaka,O.
    • Journal Title

      peer reveiwed

      Volume: Vol.19-No.4 Pages: 563-580

    • Peer Reviewed
  • [Journal Article] Sequence-dependent histone variant positioning signatures, BMC Genomics2011

    • Author(s)
      Le, N.T., Ho, T.B., Ho, B.H.
    • Journal Title

      Peer reviewed

      Volume: Vol. 11 (Suppl 4) Pages: 1-9

    • Peer Reviewed
  • [Journal Article] Enhancing Privacy in Distributed Data Clustering,Journal of Computer Science and Cybernetics2011

    • Author(s)
      Luong, T.D., Ho, T.B.
    • Journal Title

      peer Reviewed

      Volume: Vol. 26, No.2 Pages: 1-15

    • Peer Reviewed
  • [Journal Article] Discovering Relationship between Hepatitis C Virus NS5A Protein and Interferon/Ribavirin Therapy,Knowledge, Information and Creativity Support Systems KICSS2010 Revised Selected Papers2011

    • Author(s)
      Kawasaki, S., Ho, T.B., Kanda, T.
    • Journal Title

      Peer Reviewed

      Volume: LNAI6746 Pages: 79-90

    • Peer Reviewed
  • [Journal Article] Characterizing nucleosome dynamics from genomic and epigenetic information using rule induction learning, BMC enomics2009

    • Author(s)
      Le, N.T., Ho, T.B., Tran, D.H.
    • Journal Title

      Peer Reviewed

      Volume: Vol.10(Suppl.3) Pages: S27 (1-10)

    • Peer Reviewed
  • [Presentation] An Effective Method for Generating siRNA Design Rules2013

    • Author(s)
      Bui, N.T., Ho, T.B., Kawasaki, S.
    • Organizer
      The 5th Asian Conference On Intelligent Information and Database Systems, ACIID 2013(LNAI 7803 pp.196-205)
    • Place of Presentation
      Kuala Lumpur/Malasia
    • Year and Date
      20130318-20
  • [Presentation] From Clinical to Genomics Data in Hepatitis Study2012

    • Author(s)
      Ho, T.B., Takabayashi, T., Kanda, T.,Kawasaki, S., Le, T.N., Bui, N.T., Than,Q.K.
    • Organizer
      The First Asian Conference on Information Systems
    • Place of Presentation
      Siem Reap/Cambodia
    • Year and Date
      20121206-8
  • [Presentation] A Sequential Apriori Algorithm for Discriminative Design Rules of Effective siRNA Sequences2012

    • Author(s)
      Bui, N.T., Ho, T.B., Kawasaki, S.
    • Organizer
      13th International Symposium on Knowledge and Systems Science
    • Place of Presentation
      石川県金沢市
    • Year and Date
      20121119-20
  • [Presentation] Supervised dimension reduction with topic model2012

    • Author(s)
      Than, K., Pham. N.K., Nguyen, D.K., Ho,T.B.
    • Organizer
      4th Asian Conference on Machine Learning 2012
    • Place of Presentation
      Singapore/ Singapore
    • Year and Date
      20121104-6
  • [Presentation] A Semi-Supervised Method for Discriminative Motif Finding and Its Application to Hepatitis C Virus Study2012

    • Author(s)
      Le, N., Ho, T.B.
    • Organizer
      4th Asian Conference on Intelligent Information and Database Systems ACIIDS 2012
    • Place of Presentation
      Kaohsiung/Taiwan
    • Year and Date
      20120319-21
  • [Presentation] Finding HCV NS5A Discriminative Motifs for Assessment of IFN/Ribavarin Therapy Effect, Workshop Data Mining in Genomics and Proteomics2011

    • Author(s)
      Ho, T.B., Kawasaki, S., Le, N.T., Kanda,T., Le, T.N., Takabayashi, K., Yokosuka,O.
    • Organizer
      International Conference ECML/PKDD(pp.32-42)
    • Place of Presentation
      Athens/Greece
    • Year and Date
      20110905-9
  • [Presentation] Mining parallel documents across Web sites2010

    • Author(s)
      Pham, N.K., Ho, T.B.
    • Organizer
      The Sixth Asia Information Retrieval Societies Conference AIRS 2010
    • Place of Presentation
      Taipei.Taiwan
    • Year and Date
      20101201-3
  • [Presentation] Discovering Relationship between Hepatitis C Virus NS5A Protein and Interferon/Ribavirin Therapy2010

    • Author(s)
      Kawasaki, S., Ho, T.B., Kanda, T.,Yokosuka, O., Takabayashi, K., Le, T.N.
    • Organizer
      Fifth International Conference on Knowledge,Information and Creativity Support Systems KICSS'10
    • Place of Presentation
      ChiangMai/Thailand
    • Year and Date
      20101125-27
  • [Presentation] Quantitatively assessing the effect of regulatory factors on nucleosome dynamics2009

    • Author(s)
      Ho, B.H., Le, N.T., Ho, T.B.
    • Organizer
      IEEE-RIVF International Conference on Computing and Communication Technologies
    • Place of Presentation
      Hanoi/Vietnam
    • Year and Date
      20091101-4
  • [Presentation] Towards service-oriented knowledge discovery in biomedicine research2009

    • Author(s)
      Ho, T.B., Takabayashi, K., Pham, T.H. ,Nguyen, T.P., Kawasaki, S., Tran, D.H.
    • Organizer
      International Workshop on Third Generation Data Mining, ECML/PKDD 2009(pp.100-113)
    • Place of Presentation
      Bled/Slovenia
    • Year and Date
      2009-07-11
  • [Book] Knowledge Discovery (Chapter 4 of,Knowledge Technology and Science edited by Y. Nakamori)2011

    • Author(s)
      Ho, T.B.
    • Total Pages
      57-81
    • Publisher
      CRC Press and Taylor & Francis
  • [Book] Mining multiple biological data for reconstructing signal transduction networks (Data Mining: Foundations and Intelligent Paradigms edited by D.E.Holmes & L.C. Jain)2011

    • Author(s)
      Nguyen, T.P., Ho, T.B.
    • Total Pages
      163-185(380)
    • Publisher
      Springer-Verlag

URL: 

Published: 2014-08-29  

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