2011 Fiscal Year Final Research Report
Theoretical and experimental study of glutamatergic receptor mechanisms underlying orientation plasticity
Project/Area Number |
21500268
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Cognitive science
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Research Institution | The University of Electro-Communications |
Principal Investigator |
TANAKA Shigeru 電気通信大学, 大学院・情報理工学研究科, 特任教授 (70281706)
|
Co-Investigator(Renkei-kenkyūsha) |
MIYASHITA Masanobu 沼津工業高等専門学校, 制御情報工学科, 准教授 (20443038)
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Project Period (FY) |
2009 – 2011
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Keywords | 進化 / 発達 / 自己組織化 |
Research Abstract |
Using intrinsic signal optical imaging, it has been confirmed that in the visual cortex of kittens exposed to a single orientation, the representation of the exposed orientation occupied a marge cortical territory, and that there is a sensitive period during which this alteration of orientation maps occurs. In this study, using a self-organization model based on the NMDAR mechanism, we performed simulations of orientation map alteration under single-orientation exposure for a fixed period following normal visual experience. The simulations demonstrated to well reproduced the experimentally observed features of map alteration by single-orientation exposure.
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