2011 Fiscal Year Final Research Report
Evaluation of prognosis and optimal timing of valve replacement for patients with aortic regurgitation by myocardial damage and exercise capacity
| Project/Area Number |
21500494
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Tokyo Women's Medical University |
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Principal Investigator |
UENO Atsuko 東京女子医科大学, 医学部, 助教 (30277199)
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| Co-Investigator(Kenkyū-buntansha) |
TOMIZAWA Yasuko 東京女子医科大学, 医学部, 助教 (00159047)
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| Co-Investigator(Renkei-kenkyūsha) |
UETSUKA Yoshio 東京女子医科大学, 医学部, 教授 (40147418)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 大動脈弁閉鎖不全症 / 心肺運動負荷試験 / 運動耐容能 / 運動療法 / 心拍応答 / 心不全 / 予後 |
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| Research Abstract |
Severe aortic regurgitation(AR) patients show heart failure(HF). The prognosis of HF does not correlation with left ventricular ejection fraction(LVEF). We examined exercise capacity and heart rate response by cardiopulmonary exercise testings to patients with heart failure including patients with aortic regurgitation, and also predicted their prognosis. As a result, we showed the positive correlation between peak O2 consumption and heart rate response. The case showed that whose heart rate decreased at rest by optimal exercise therapy. Therefore we suggested the possibility that exercise therapy improve exercise capacity for the patients with heart failure.
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