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2011 Fiscal Year Final Research Report

Analysis of muscle functions in exercise by producing exercise-reporter animals.

Research Project

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Project/Area Number 21500629
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionKanazawa University

Principal Investigator

HITOMI Yoshiaki  金沢大学, 医学系, 准教授 (70231545)

Co-Investigator(Kenkyū-buntansha) NAKAMURA Hiroyuki  金沢大学, 医学系, 教授 (30231476)
KAMBAYASHI Yasuhiro  金沢大学, 医学系, 講師 (20345630)
Co-Investigator(Renkei-kenkyūsha) HIBINO Yuri  金沢大学, 医学系, 助教 (40362008)
Project Period (FY) 2009 – 2011
Keywordsスポーツ生化学
Research Abstract

We investigated the usability of transgenic animals, harboring a reporter gene encoding a short half-life reporter protein driven by the exercise-inducible promoter, on exercise and skeletal muscle study. The expression levels of reporter proteins were not necessarily enough to monitor the effect of exercise on individual muscle activity. However, these animals provide important insights in designing an exercise-reporter transgene to create an exercise-reporter transgenic animal.

  • Research Products

    (11 results)

All 2011 2010 2009

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (3 results) Book (1 results)

  • [Journal Article] Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells2011

    • Author(s)
      Sugimoto N, Miwa S, Ohno Shosaku T, Tsuchiya H, Hitomi Y, Nakamura H, Tomita K, Yachie A, Koizumi S
    • Journal Title

      Neurosci Lett

      Volume: Vol.497 Pages: 55-59

    • Peer Reviewed
  • [Journal Article] The Differences in the Involvements of Loci of Promoter Region and Ile50Val in Interleukin-4 Receptor alpha Chain Gene between Atopic Dermatitis and Japanese Cedar Pollinosis2011

    • Author(s)
      Tanaka T, Hitomi Y, Kambayashi Y, Hibino Y, Fukutomi Y, Shibata A, Sugimoto N, Hatta K, Eboshida A, Konoshita T, Nakamura H
    • Journal Title

      Allergol Int

      Volume: Vol.61 Pages: 57-63

    • Peer Reviewed
  • [Journal Article] C-reactive protein is associated with cigarette smoking-induced hyperfiltration and proteinuria in an apparently healthy population2010

    • Author(s)
      Sauriasari R, Sakano N, Wang DH, Takaki J, Takemoto K, Wang B, Sugiyama H, Sato Y, Takigawa T, Takahashi N, Kanbara S, Hitomi Y, Nakamura H, Ogino K
    • Journal Title

      Hypertens Res

      Volume: Vol.33 Pages: 1129-1136

    • Peer Reviewed
  • [Journal Article] Association between altered systemic inflammatory interleukin-1beta and natural killer cell activity and subsequently agitation in patients with Alzheimer disease2010

    • Author(s)
      Higuchi M, Hatta K, Honma T, Hitomi YH, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Nakamura H
    • Journal Title

      Int J Geriatr Psychiatry

      Volume: Vol.25 Pages: 604-611

    • Peer Reviewed
  • [Journal Article] Common risk factors for changes in body weight and psychological well-being in Japanese male middle-aged workers2009

    • Author(s)
      Sagara T, Hitomi Y, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Ogino K, Hatta K, Nakamura H
    • Journal Title

      Environ Health Prev Med

      Volume: Vol.14 Pages: 319-327

    • Peer Reviewed
  • [Journal Article] Preparation and Characterization of a Polyclonal Antibody against Brominated Protein2009

    • Author(s)
      Kambayashi Y, Ogino K, Takemoto K, Imagama T, Takigawa T, Kimura S, Hibino Y, Hitomi Y, Nakamura H
    • Journal Title

      J Clin Biochem Nutr

      Volume: Vol.44 Pages: 95-103

    • Peer Reviewed
  • [Journal Article] Efficient assay for total antioxidant capacity in human plasma using a 96-well microplate2009

    • Author(s)
      Kambayashi Y, Binh NT, W Asakura H, Hibino Y, Hitomi Y, Nakamura H, Ogino K
    • Journal Title

      J Clin Biochem Nutr

      Volume: Vol.44 Pages: 46-51

    • Peer Reviewed
  • [Presentation] マウスビタミンC代謝に対する急性運動の影響2011

    • Author(s)
      人見嘉哲、神林康弘、中村裕之, 他7名
    • Organizer
      第81回日本衛生学会学術総会
    • Place of Presentation
      誌上開催
    • Year and Date
      20110300
  • [Presentation] ストレスによるマウス血漿総抗酸化能、抗酸化物質濃度の変化2010

    • Author(s)
      人見嘉哲、辻本藤太郎、神林康弘、中村裕之, 他5名
    • Organizer
      第9回分子予防環境医学研究会
    • Place of Presentation
      東京大学医学部1号館、東京
    • Year and Date
      2010-01-23
  • [Presentation] Lipopolysaccharide(LPS)投与マウス敗血症モデルにおける血漿中抗酸化物質濃度と総抗酸化能の変化2009

    • Author(s)
      辻本藤太郎、人見嘉哲、神林康弘、中村裕之, 他3名
    • Organizer
      第7回日本予防医学会学術総会
    • Place of Presentation
      千葉大学西千葉キャンパスけやき会館、千葉
    • Year and Date
      2009-12-12
  • [Book] 特定健康診査in予防医学指導士テキスト2009

    • Author(s)
      人見嘉哲
    • Total Pages
      197-206
    • Publisher
      日本予防医学会

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Published: 2013-07-31   Modified: 2014-12-10  

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