2011 Fiscal Year Final Research Report
Analysis of the effects of the nutritional composition on obesity, glucose and lipid metabolism, and atherosclerosis
Project/Area Number |
21500678
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied health science
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Research Institution | University of Tsukuba |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI Akimitsu 筑波大学, 医学医療系, 准教授 (70344893)
YATO Shigeru 筑波大学, 医学医療系, 講師 (50451703)
KOBAYASHI Kazuto 筑波大学, 医学医療系, 講師 (30455935)
|
Project Period (FY) |
2009 – 2011
|
Keywords | 生活習慣病 |
Research Abstract |
The effects of staple foods on the postprandial hyperglycemia and hyperlipidemia differed between rice and white bread in patients with type 2 diabetes. Eating white rice significantly raised postprandial glucose level in comparison with eating white bread. On the other hand, eating white bread significantly raised postprandial triglycerides level more than eating white bread. These data suggest that source of carbohydrate affect not only postprandial glucose level but also postprandial hyperlipidemia. Intima-media thickness (IMT) in carotid ultrasound could predict coronary artery disease detected by coronary CT angiography. There was no association between coronary artery plaque and serum fatty acid composition, although sample size of this study was small. A prospective study in large sample size is needed to investigate the relationship between coronary artery disease and serum fatty acid composition.
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Research Products
(5 results)
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[Presentation] フラミンガムリスクスコア、UKPDSリスクエンジン、max-IMT、LDL/HDL 比による冠動脈病変予測能に関する検討2012
Author(s)
藤原和哉, 鈴木浩明, 佐藤明, 大崎芳典, 尾本美代子, 豊崎晶子, 平安座依子, 児玉暁, 齋藤和美, 小林和人, 高橋昭光, 矢藤繁, 山田信博, 曽根博仁, 島野仁
Organizer
第55回日本糖尿病学会年次学術集会
Place of Presentation
横浜
Year and Date
2012-05-18
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[Presentation] Impact of serumlipid level on number of vulnerable coronary plaque (VP) detected by CT angiography (CTA) in asymptomatic patients with type 2 diabetes (T2DM)2011
Author(s)
Kazuya Fujihara, Hiroaki Suzuki, AkiraSato, Tomoko Ishizu, Yoriko Heianza, Satoru Kodama, Kazumi Saito, Kazuto Kobayashi, Shigeru Yato, Akimitsu Takahasi, Nobuhiro Yamada, Hirohito Sone, Hitoshi Shimano
Organizer
第43回日本動脈硬化学会総会・学術集会
Place of Presentation
札幌
Year and Date
2011-07-16
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[Presentation] Evaluation of Clinical Predictors of Vulnerable Coronary Plaque Detected by CT Angiography in Asymptomatic Patients with type 2 Diabetes (T2DM)2011
Author(s)
Kazuya Fujihara, Hiroaki Suzuki, Akira Sato, Yoriko Heianza, Satoru Kodama, Kazumi Saito, Kazuto Kobayashi, Akimitsu Takahashi, Shigeru Yatou, Nobuhiro Yamada, Hirohito Sone, Hitoshi Shimano
Organizer
71st scientific sessions of American Diabetes Association, San Diego, USA
Year and Date
2011-06-27
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[Presentation] CT coronary angiography (CTA)による冠動脈不安定プラーク(VP)と関連する臨床指標に関する検討2011
Author(s)
藤原和哉, 鈴木浩明, 佐藤明, 大崎芳典, 尾本美代子, 豊崎晶子, 平安座依子, 児玉暁, 斎藤和美, 小林和人, 矢藤繁, 高橋昭光, 山田信博, 曽根博仁, 島野仁
Organizer
第54回日本糖尿病学会年次学術集会
Place of Presentation
札幌
Year and Date
2011-05-20
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