2011 Fiscal Year Final Research Report
Screening of food components for the prevention of alcoholic liver diseases and their application
| Project/Area Number |
21500783
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Osaka City University |
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Principal Investigator |
YUASA Akiko 大阪市立大学, 大学院・生活科学研究科, 准教授 (90295709)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 健康と食生活 / 生活習慣病 / 食品成分 / アルコール性肝疾患 / 肝細胞 / 肝星細胞 |
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| Research Abstract |
We studied the protection against ethanol-induced liver injury by various food components. The goal of this study is to propose a utilization of them into our dietary habits for the prevention of the disease. We examined the protective effect of various food components by using in vitro cell culture models for hepatitis and for liver cirrhosis and an in vivo animal model for liver disease, which were developed by us. Then we got the following results. We found that Ecklonia cava extract, extract from Tamatsukuri-kuromon Shirouri, sesame lignin and Mate tea extract have the protective effects for ethanol-induced liver injury on our in vitro and in vivo models and suggested that the ingestion of these components is useful for our healthy life.
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[Remarks] 新聞掲載(1)読売新聞(平成24年2月26日付)大学の企画ページ新聞掲載
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[Remarks] (2)食品化学新聞(平成23年7月14日付)「食品成分による生活習慣病の予防」新聞掲載
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[Remarks] (3)産経新聞(平成21年5月30日付)「生活習慣病を予防する食品成分-玉造黒門越瓜の効果-」新聞掲載
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[Remarks] TV出演(1)朝日放送番組名「キャスト」(平成24年3月13日放送) TV出演
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[Remarks] (2)朝日放送番組名「おはよう朝日」(平成24年3月7日放送)マテ茶特集TV出演
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[Remarks] (3)韓国国営放送(KBSテレビ)番組名「Science Cafe」(平成21年11月7日放送)「カジメ(Ecklonia cava)抽出物によるアルコール性肝疾患予防効果とそのメカニズムについて」TV出演
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