2011 Fiscal Year Final Research Report
Analysis for Dynamics on High Order Structure of Protein
| Project/Area Number |
21540417
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KATO Koichi 名古屋市立大学, 薬学研究科, 教授 (20211849)
MORIMOTO Yukio 京都大学, 原子炉実験所, 教授 (80200450)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 生物物理 |
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| Research Abstract |
We established an analysis method for dynamics of high order structure of protein by Small-Angle Neutron Scattering utilizing deuterated proteins and solvent contrast variation technique. With the method, we found the subunit exchange between the aggregates consisting ofα7-subunits which are one of subunits of the 20S proteasome, and analyzed its kinetics.
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