2011 Fiscal Year Final Research Report
New analytical method on channel transports across bilayer lipid membranes
| Project/Area Number |
21550079
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Kyoto University |
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Principal Investigator |
SHIRAI Osamu 京都大学, 大学院・農学研究科, 准教授 (40355011)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 状態分析 |
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| Research Abstract |
New analytical method on channel transports across bilayer lipid membranes was proposed by considering mass balance and electroneutrality. When the ion channel serves in the membrane, not only the transport of the target ion but also those of coexsisting ions should be evaluated. The ion-transport property was not controlled by only the relation between the ion size and the pore-size of the ion channel. It was proved that the distribution coefficients of both the target ion and the counter ion and their diffusion coefficients within the membrane were important factors.
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[Journal Article]2009
Author(s)
Osamu Shirai, Shunsuke Ozaki, Jun Onishi, N. Kozai, Toshihiko Ohnuki and Kenji Kano
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Journal Title
Chemistry Letters
Volume: 38
Pages: 1038-1039
DOI
Peer Reviewed
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