2011 Fiscal Year Final Research Report
An Efficient Access to Chiral Compounds via Asymmetric Hydrogenation of Polar Functional Groups
| Project/Area Number |
21550096
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kyushu University |
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Principal Investigator |
ITO Masato 九州大学, 先導物質化学研究所, 准教授 (20293037)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 触媒設計・反応 / 不斉合成反応 |
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| Research Abstract |
Novel molecular catalysts have been developed for the straightforward hydrogenation of a range of carboxylic acid derivatives under mild conditions. Modular design of chiral molecular catalysts could provide direct access to stereochemically well-defined moleculres, which might otherwise have required a detour to reach. Another important finding in this study is that the coexistence of inorganic base has led to dramatic improvement in their catalytic activity.
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[Presentation] Ryo Watari, Takashi Ootsuka, Akira Shiibashi, Akio Himizu, Masato Ito, Hydrogenation of Esters and Carboxamides Promoted by Bifunctional Cp^* Ru Catalysts2011
Author(s)
Ryo Watari, Takashi Ootsuka, Akira Shiibashi, Akio Himizu, Masato Ito, Takao Ikariya
Organizer
16^<th> IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
Place of Presentation
Shanghai, China
Year and Date
2011-07-24
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