2011 Fiscal Year Final Research Report
Development of Iridium-Catalyzed Highly Selective Organic Synthesis
| Project/Area Number |
21550107
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Aoyama Gakuin University |
|---|
Principal Investigator |
TAKEUCHI Ryo 青山学院大学, 理工学部, 教授 (00216871)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ONODERA Gen 青山学院大学, 理工学部, 助教 (90433698)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | イリジウム / ルイス酸 / アルドール反応 / マンニッヒ反応 / 付加環化反応 / アルキン / 2-ピリドン / ピリジン |
|---|
| Research Abstract |
Iridium-catalyzed synthetic reaction hasbeen less developed than cobalt-, rhodium-, ruthenium-and palladium-catalyzed synthetic reaction. During this project, we have developed the following novel catalysis of iridium complex.(1) Cationic iridium complex is a new efficient Lewis acid catalyst for Mukaiyama aldol reaction and Mannich reaction.(2) Neutral iridium complex/biaryldiphosphine is an efficient catalyst for[2+2+2] cycloaddition ofα,ω-diynes with isocyanates and nitrilesto give heterocyclic compounds.
|
