2011 Fiscal Year Final Research Report
Development of Carbohydrate-Silicon Functional Material to Detect Avian Influenza Virus
| Project/Area Number |
21550152
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemistry related to living body
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| Research Institution | Saitama University |
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Principal Investigator |
HATANO Ken 埼玉大学, 大学院・理工学研究科, 准教授 (40332316)
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| Project Period (FY) |
2009 – 2011
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| Keywords | カルボシランデンドリマー / シアリルラクトース / 糖鎖クラスター効果 / インフルエンザ / ウイルス |
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| Research Abstract |
We succeeded a synthesis of a novel carbosilane dendrimer functionalized aggregation-induced emission (AIE) active 2, 3, 4, 5 tetraphenyl1silacyclo-pentadiene at the core and periphery functionalized avian influenza virus binding 3'-sialyllactose as an avian inluruenza detection agent. Detection test of the virus using the dendrimer prepared here is currently in progress.
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[Journal Article]2009
Author(s)
B. P. Guo, S. Teneberg, R. Munch, D. Terunuma, K. Hatano, K. Matsuoka, J. Angstrom, T. Boren, S. Bergstrom
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Journal Title
Proc. Natl. Acad. Sci
Volume: 106(46)
Pages: 19280-19285
DOI
Peer Reviewed
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[Journal Article] Systematic syntheses of influenza neuraminidase inhibitors : A series of carbosilane dendrimers uniformly functionalized with thioglycoside-type sialic acid moieties2009
Author(s)
J.-I. Sakamoto, T. Koyama, D. Miyamoto, S. Yingsakmongkon, K. I. P. J. Hidari, W. Jampangern, T. Suzuki, Y. Suzuki, Y. Esumi, T. Nakamura, K. Hatano, D. Terunuma, K. Matsuoka
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Journal Title
Bioorg. Med. Chem
Volume: 17
Pages: 5451-5464
DOI
Peer Reviewed
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