Formation and Osteoconductivity of Anodized TiO2 Coating with Functional Group

2011 Fiscal Year Final Research Report

• Project/Area Number: 21560719
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Structural/Functional materials
• Research Institution: Nagoya University
• Principal Investigator: KURODA Kensuke 名古屋大学, 工学研究科, 准教授 (00283408)
• Co-Investigator(Kenkyū-buntansha): OKIDO Masazumi 名古屋大学, 工学研究科, 教授 (50126843) ; ICHINO Ryoichi 名古屋大学, エコトピア科学研究所, 教授 (70223104)
• Project Period (FY): 2009 – 2011
• Keywords: チタニア / 親水性 / 官能基 / 湿式プロセス / 生体材料 / 骨伝導性 / 動物埋植試験

Research Abstract

Titania-coated titanium implants were formed using anodizing processing in various kinds of solutions. These TiO2 fims had anion, cation and/or functional groups, which were existed in the aqueous solutions used in anodizing. Titanium rods with TiO2 coating were implanted in rats tibia for 14 days, and osteoconductivity was evaluated from the amount of hard tissue formed on the implants. As a result, it was clear that anion, cation and/or functional groups in the films did not influence on the osteoconductivity. However, their osteoconductivity was strongly depended on the hydrophilicity/hydrophobicity of TiO2 surface. That is to say that the hydrophilicity surface had high osteoconductivity.

Research Products

• [Journal Article] Formation of Amorphous TiO_2 Film on Ti Using Anodizing in Concentrated H_3PO_4 Aqueous Solution and Its Osteoconductivity (2012)
  • Author(s): D. Yamamoto, T. Iida, K. Kuroda, R. Ichino, M. Okido, A. Seki
  • Journal Title: Mater. Trans. Volume: Vol.53, 2012, No.3 Pages: 508-512
  • DOI: DOI:10.2320/matertrans.M2011234
  • Peer Reviewed
• [Journal Article] Osteoconductive TiO_2 coating on Titanium using Anodizing in High Content Phosphoric Acid (2012)
  • Author(s): K. Kuroda, R. Ichino, M. Okido
  • Journal Title: Mater. Sci Volume: Vol.706-709 Pages: 538-542
  • DOI: DOI:10.4028/www.scientific.net/MSF.706-709.538
  • Peer Reviewed
• [Journal Article] Anodic Oxide Coatings on Ti Alloys and Their Osteoconductivity (2012)
  • Author(s): D. Yamamoto, K. Kuroda, R. Ichino, M. Okido
  • Journal Title: Mater. Sci. Forum Volume: Vol.706-709 Pages: 612-616
  • DOI: DOI:10.4028/www.scientific.net/MSF.706-709.612
  • Peer Reviewed
• [Journal Article] HAp Coating of Titanium Implants using Hydroprocessing and Evaluation of Their Osteoconductivity (2012)
  • Author(s): K. Kuroda, M. Okido
  • Journal Title: Bioinorg. Chem. Applications Volume: Vol.2012 Pages: 7
  • DOI: DOI:10.1155/2012/730693
  • Peer Reviewed
• [Journal Article] Osteoconductivity of Anodized Titanium with Controlled Micron-Level Surface Roughness (2011)
  • Author(s): D. Yamamoto, I. Kawai, K. Kuroda, R. Ichino, M. Okido, A. Seki
  • Journal Title: Mater. Trans Volume: Vol.52, No.8 Pages: 1650-1654
  • DOI: DOI:10.2320/matertrans.M2011049
  • Peer Reviewed
• [Presentation] (2012)
  • Author(s): 黒田健介,有井一志,山本大,市野良一,興戸正純
  • Organizer: 第25回歯科チタン学会学術講演会
  • Place of Presentation: 愛知学院大学(愛知県)
  • Year and Date: 20120218-20
• [Presentation] BMMP-12 (2012)
  • Author(s): M. Sakakibara, K. Kuroda, R. Ichino, M. Okido
  • Organizer: Jan
  • Place of Presentation: 名古屋大学(愛知県)
  • Year and Date: 20120124-27
• [Presentation] (2011)
  • Author(s): 有井一志,黒田健介,市野良一,興戸正純
  • Organizer: 日本金属学会・秋期講演大会
  • Place of Presentation: 宜野湾(沖縄)
  • Year and Date: 20111107-09
• [Presentation] (2011)
  • Author(s): 山本大,黒田健介,市野良一,興戸正純
  • Organizer: 材料と環境討論会
  • Place of Presentation: 名古屋大学(愛知県)
  • Year and Date: 20110928-30
• [Presentation] (2011)
  • Author(s): 田島雄太,黒田健介,市野良一,興戸正純
  • Organizer: 軽金属学会・第120回春期大会
  • Place of Presentation: 名古屋大学(愛知県)
  • Year and Date: 20110520-22
• [Remarks]
  • URL: http://f2.numse.nagoya-u.ac.jp/theme01.html