2011 Fiscal Year Final Research Report
Evolutionary analysis of duplicated genes enhancer in teleost lineage by using fugu embryos.
| Project/Area Number |
21570218
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | Otx / ゲノム / フグ / 発生進化 |
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| Research Abstract |
We compared the organizer enhancer activities between Fugu Otx2a and Otx2b which are duplicated by teleost specific genome duplication. For this purpose, we adapted the successful induction of reporter gene DNA and morpholino antisense oligo molecules into the fertilized eggs of Takifugu niphobles(Kusafugu). The feasibility to perform transgenesis is an important step to establish T. niphobles as new model in evolution and developmental research.
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