2011 Fiscal Year Final Research Report
Molecular and Cellular mechanisms of germline mother cell regeneration in colonial tunicates
Project/Area Number |
21570227
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Developmental biology
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Research Institution | Kochi University |
Principal Investigator |
KAWAMURA Kazuo 高知大学, 教育研究部・自然科学系, 教授 (30136361)
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Co-Investigator(Kenkyū-buntansha) |
SUNANAGA Takeshi 高知大学, 教育研究部・自然科学系, 講師 (20448393)
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Project Period (FY) |
2009 – 2011
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Keywords | 幹細胞 / 生殖細胞 / 再生 / 無性生殖 / ホヤ |
Research Abstract |
Ascidians are the marine invertebrate that is most closely related to vertebrates. Colonial tunicates propagate by means of both sexual and asexual reproduction, and they can regenerate gonads and germ cells even though gonad components are completely extirpated from the colony. This study has disclosed that Myc/ Piwi-expressing cells are reserved in the hemocoel, and that they respond to BMP to express germline-specific gene Vasa, enabling the regeneration of germline cells and tissues.
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Research Products
(16 results)
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[Journal Article] Tunicate cytostatic factor TC14 induces the polycomb group gene Eed and histone modification through Ca^<2+> binding and protein dimerization2012
Author(s)
Kawamura, K., Takakura, K., Mori, D., Ikeda, K., Nakamura, A. and Suzuki, T.
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Journal Title
BMC Cell Biol
Volume: 13
Pages: 1-13
Peer Reviewed
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[Journal Article] Looking for putative phenoloxidases of compound ascidians : haemocyanin-like proteins in Polyandrocarpa misakiensis and Botryllus schlosseri
Author(s)
Ballarin, L., Franchi, N., Schiavon, F., Tosatto, S. C. E, Mi. eti., I. and Kawamura, K.
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Journal Title
Peer Reviewed
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