2011 Fiscal Year Final Research Report
Beet dietary fiber decreased body fat and increased hypothalamic gene expression of leptin receptor in rats
| Project/Area Number |
21580143
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Ehime University |
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Principal Investigator |
KISHIDA Taro 愛媛大学, 農学部, 准教授 (80304658)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 食物繊維 / 摂取エネルギー / レプチン / 視床下部 / ラット |
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| Research Abstract |
Lack of leptin receptor(Ob-Rb) function canceled effects of dietary beet fiber on energy intake and body fat. Ob-Rb might play predominant role in the mechanism. Dietary BF increased hypothalamic Ob-Rb gene expression and modified appetite regulating factors. Vagus nerve blocking technique revealed that brain-gut connection via vagus nerve might not be necessary to effects of dietary beet fiber on energy intake and body fat.
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