2011 Fiscal Year Final Research Report
Establishment of the diagnostic technique of nutritional status with the nutriproteomics of the skin
| Project/Area Number |
21580156
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Tokyo University of Agriculture |
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Principal Investigator |
OISHI Yuichi 東京農業大学, 応用生物科学部, 教授 (00313073)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 二次元電気泳動 / ニュートリプロテオミクス / 表皮タンパク質 / MALDI-TOF-MS |
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| Research Abstract |
I focused on the proteomic analysis of epidermal proteins because of developing a new clinical examination technique to evaluate a nutrition status. I investigated the change in epidermal proteins in rats fed diets with different protein quality and quantity(casein diet, gluten diet and protein-free diet) using 2-two-dimensional electrophoresis(2-DE). This 2-DE result showed that 21 types of proteins underwent a change by the diets with low protein quality containing Ras-related protein Rab-6A, NADH dehydrogenase, α-enolase.
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