2011 Fiscal Year Final Research Report
Studies on mechanisms for the crosslinking formation in fish collagen-Cause investigation of the chemical instability in fish collagen
| Project/Area Number |
21580252
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fisheries chemistry
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| Research Institution | Fukui Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | トラフグ / コラーゲン / コラーゲン修飾酵素 / LH |
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| Research Abstract |
The chemical instability of fish collagen, higher solubility to dilute acetic acid, indicates that the intermolecular cross-links in fish collagen differ from those in mammal collagen in quantity and/or quality. In fish, however, little information is available on the collagen cross-links, and the mechanism of cross-link formation has not been clear. To obtain the fundamental information on the regulatory mechanism of collagen-cross-linking pathway in fish, the author conducted cDNA cloning of fugu Takifugu rubripes LHs(LH1, 2a, 2b and 3) and performed expression analysis in the adult tissues and the embryos.
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