2011 Fiscal Year Final Research Report
Morpho-functional relationship between myostatin and muscle spindle in bovine skeletal muscles.
| Project/Area Number |
21580341
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | 筋線維型 / 筋紡錘 / ミオスタチン / 筋運動制御 / ウシ / 筋小胞体カルシウムポンプ / カルパイン |
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| Research Abstract |
Morpho-functional relationship between myostatin and muscle spindle was investigated in bovine skeletal muscles, using double-muscled cattle"Grass-field shorthorn". Though this study was stricken seriously by the Great East Japan Earthquake, we found that slow muscles contained many type I myofibers exhibited lower expression of myostatin than fast muscle did. Furthermore our results suggested that a calcium ion signaling in myofiber might play a crucial role in myofiber type fast-to-slow transformation.
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