2011 Fiscal Year Final Research Report
Why do not obese bears suffer fatty liver?-Study on mechanism for accumulation of body fat during pre-hibernation period
| Project/Area Number |
21580355
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Hokkaido University |
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Principal Investigator |
TSUBOTA Toshio 北海道大学, 大学院・獣医学研究科, 教授 (10207441)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMOZU Rumichito 北海道大学, 大学院・獣医学研究科, 助教 (50507168)
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| Project Period (FY) |
2009 – 2011
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| Keywords | クマ / 冬眠 / 肥満 / 体脂肪 / グルコース / 静注糖負荷試験 / インスリン / 脂肪肝 |
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| Research Abstract |
This study was conducted in Ani Mataginosato Bear Park, Kitaakita-shi, Akita Prefecture in order to know why obese bears do not suffer fatty liver even though they get 30-40% fat of body weight and to investigate a feature mechanism for accumulation of body fat. Under anesthetized condition, measurements of blood concentrations of carbohydrate and fat, intravenous glucose tolerance tests and adipose tissue biopsies were performed for this study. As results, it is concluded that increase of body fat accumulation during pre-hibernation period is controlled by physiological and metabolic mechanism as well as hyperphagia in Japanese black bears
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[Journal Article] Change in body weight of mothers and neonates and in milk composition during denning period in captive Japanese black bears (Ursus thibetanus japonicus)2009
Author(s)
Iibuchi, R., Nakano, N., Nakamura, T., Urashima, T., Shimozuru, M., Murase, T. & Tsubota, T
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Journal Title
Jpn. J. Vet. Res
Volume: 57
Pages: 13-22
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[Presentation] Physiological and endocrinological mechanism for nutritional condition and reproduction related to hibernation in the Japanese black bear (Ursus thibetanus japonicas)2009
Author(s)
Tsubota, T., Nakamura, S., Iibuchi, R.,Kamine, A., Shimozuru, M
Organizer
International Symposium on Conservation of Asiatic Black Bear
Place of Presentation
Taipei, Taiwan
Year and Date
2009-11-21
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