2011 Fiscal Year Final Research Report

A new diagnostic method for canine leptospirosis

Research Project

Project/Area Number	21580391
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Clinical veterinary science
Research Institution	Yamaguchi University
Principal Investigator	OKUDA Masaru 山口大学, 農学部, 教授 (10325243)
Project Period (FY)	2009 – 2011
Keywords	レプトスピラ / ラテックス凝集法 / 犬 / 人獣共通感染症
Research Abstract	Leptospirosis is a zoonotic disease. Since the canine one may be lethal, it must be diagnosed in the early stage. However, there is no quick diagnostic method. A purpose of this study is developing a new convenient method for the canine leptospirosis. We identified fas1 and MaoC proteins as important antigens by analysis of leptospiral outer membrane proteins, and made latex beads for agglutination assays using their recombinant proteins. Our data suggest that this method is useful in the serological diagnosis of the canine leptospirosis.